An observational single-center study of nivolumab in Indian patients with recurrent advanced non-small cell lung cancer

Conclusion: Data from our study suggest nivolumab is well-tolerated and effective in Indian patients with recurrent advanced NSCLC after failure of the multiple first lines of platinum-based combination chemotherapy.
Source: Indian Journal of Cancer - Category: Cancer & Oncology Authors: Source Type: research

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Publication date: Available online 20 November 2019Source: Journal of Advanced ResearchAuthor(s): Sohail Mumtaz, Pradeep Bhartiya, Neha Kaushik, Manish Adhikari, Pradeep Lamichhane, Su-Jae Lee, Nagendra Kumar Kaushik, Eun Ha ChoiAbstractOver the past few decades, microwave (MW) radiation has been widely used, and its biological effects have been extensively investigated. However, the effect of MW radiation on human skin biology is not well understood. We study the effects of pulsed high-power microwaves (HPMs) on melanoma (G361 and SK-Mel-31) and normal human dermal fibroblast (NHDF) cells. A pulsed power generator (Chundo...
Source: Journal of Advanced Research - Category: Research Source Type: research
We are pleased to invite investors and analysts to participate in a live audio webcast and conference call on Monday, 16 December 2019, highlighting Roche data presented at the San Antonio Breast Cancer Symposium in San Antonio, Texas, from 10th - 14th December.
Source: Roche Investor Update - Category: Pharmaceuticals Source Type: news
Journal of Medicinal Food, Ahead of Print.
Source: Journal of Medicinal Food - Category: Nutrition Authors: Source Type: research
CONCLUSIONS Our data demonstrate an oncogenic role of miR-652 in uveal melanoma, showing that miR-652 may be a useful biomarker for prediction of prognosis for patients with uveal melanoma. PMID: 31740654 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
CONCLUSIONS Early detection of SB CD without complications remains difficult even if advanced modalities are introduced. Our hypothesis is that the fecal occult blood test and routine blood test should be administered to patients with abdominal pain or gastrointestinal manifestations. Once the patients are found to have GI bleeding or anemia, they would be further examined according to the guideline and SBCE would be used in the early stage of SB CD. PMID: 31738744 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
CONCLUSIONS Our findings suggest that PLR is a useful parameter to consider when hematologists attempt to assess the risk of recurrence in ITP patients receiving first-line therapy, and the nonlinearity of PLR and ITP recurrence risk must be fully considered when constructing predictive models. PMID: 31735908 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Authors: Pandit A, Gupta N, Madan K, Bharti SJ, Kumar V Abstract Pulmonary alveolar proteinosis (PAP) is an uncommon lung disease characterized by excessive accumulation of pulmonary surfactant that usually requires treatment with whole-lung lavage. A 47-year-old female presented with history of dry cough and breathlessness for past 6months. Chest radiograph demonstrated bilateral alveolar shadows and high resolution computerized tomography thorax showed crazy paving pattern. Broncho-alveolar lavage (BAL) and transbronchial lung biopsy confirmed a diagnosis of PAP. Due to worsening hypoxemia and respiratory failure...
Source: Ghana Medical Journal - Category: African Health Tags: Ghana Med J Source Type: research
This study identified correlates of good screening performance for three common cancers, while weighing them against the backdrop of existing knowledge, to enable policy makers and healthcare providers focus appropriately to close the gaps that exist in cancer screening in our locale. Study design: Cross-sectional design. Setting: Tertiary health facility. Participants: Workers at Delta State University Teaching Hospital, Nigeria. Results: Females had significantly better knowledge of cervical cancer, p
Source: Ghana Medical Journal - Category: African Health Tags: Ghana Med J Source Type: research
Employing multiple artificial intelligence (AI) algorithms to attack a task...Read more on AuntMinnie.comRelated Reading: Practical Considerations of AI: Part 6 -- Ready, fire, aim Deep-learning algorithm bolsters lung cancer detection AI needs robust clinical evaluation in healthcare Deep-learning model characterizes PET/CT findings Can AI find brain hemorrhage as well as radiologists?
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Publication date: Available online 20 November 2019Source: Indian Heart JournalAuthor(s): Shaimaa MostafaAbstractBackgroundFew studies have evaluated right ventricle systolic function in different categories of heart failure despite its effect on outcomes.Methods and resultssingle-centre, cross-sectional study included 150 patients, 50 patients in each category of HF: group I, preserved; group II, mid-range, group III reduced ejection fraction. Left ventricular systolic function was assessed by 3D echo, and right ventricular systolic function was assessed by fraction area change (FAC), tricuspid annular plane systolic excu...
Source: Indian Heart Journal - Category: Cardiology Source Type: research
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