Hypoxia-Inducible Factor-1 α (HIF-1α) Promotes Hypoxia-Induced Invasion and Metastasis in Ovarian Cancer by Targeting Matrix Metallopeptidase 13 (MMP13).

CONCLUSIONS</strong> This study suggests that HIF-1alpha promotes ovarian cancer cell invasion through a MMP13 mechanism. It might be an effective strategy targeting HIF-1alpha - MMP13 to inhibit invasion and metastasis of ovarian cancer. PMID: 31587013 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research