Evaluation of the epidemiological and clinical characteristics of central nervous system infections in adults in the West Pannonian region.

[Evaluation of the epidemiological and clinical characteristics of central nervous system infections in adults in the West Pannonian region]. Orv Hetil. 2019 Oct;160(40):1574-1583 Authors: Fehér Z, Toldy E, Schneider F Abstract Introduction: Despite advancements in diagnostic capabilities and the availability of effective antimicrobial agents, community-acquired infections of the central nervous system (CNS) are still associated with high mortality rates. Aim: To assess the epidemiological and clinical characteristics of community-acquired CNS infections treated in the West Pannonian region between 2010 and 2016. Method: Clinical data of 176 patients were retrospectively analysed in two age cohorts: 15 to 65 and more than 65 years of age. Results: Neuroinfections were found to be bacterial in 81, viral in 91, parasitic in 1 and mixed in 3 cases during the observation period. The most frequent bacterial pathogens isolated were Streptococcus pneumoniae (20%) and Borrelia burgdorferi (16%). The most frequent viral pathogens isolated were tick-borne encephalitis virus (37%), herpes simplex virus (10%) and enterovirus (7%). Aetiology was unknown in 40 percent of all cases. The average incidence rate was 9.8/100 000 person/year with a mortality rate of 12%. In the cohort of patients aged>65 years, significantly higher frequencies of immunocompromising factors, lower Glasgow Coma Scale values at admission and confusion were observed (p-values: 0.008, ...
Source: Orvosi Hetilap - Category: General Medicine Authors: Tags: Orv Hetil Source Type: research

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Authors: Ben-Harari RR Abstract Introduction: Infection with Toxoplasma gondii (T. gondii) causes the disease toxoplasmosis in humans and animals. Oral transmission alone may not explain the widespread distribution of this parasite over large species of host animals and geographic areas. Areas covered: Limited studies indicate the potential role of ticks in the distribution of T. gondii. The possibility of transmission of T. gondii has been demonstrated in Dermacentor variabilis, Dermacentor andersoni, Amblyomma americanum, Dermacentor reticulatus, Ixodes ricinus, Ixodes amblyomma, Amblyomma cajennense, Ornithodoru...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
Publication date: October 2019Source: Journal of Comparative Pathology, Volume 172Author(s): P. Wohlsein, H. Seibel, A. Beineke, W. Baumgärtner, U. SiebertSummaryHearing represents the major sense in harbour porpoises (Phocoena phocoena) and impairment of hearing has a great impact on the survival of these animals. In this communication, some anatomical and histological aspects of the tympanoperiotic complex of harbour porpoises are presented. In addition, the ears of 21 incidentally bycaught or stranded freshly dead harbour porpoises of different age groups and sex were investigated histologically. At the entrance to...
Source: Journal of Comparative Pathology - Category: Pathology Source Type: research
ConclusionThe seasonal distribution of febrile seizures was high from late spring to summer, and influenza virus and enterovirus were most frequently associated.
Source: Seizure - Category: Neurology Source Type: research
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Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Viruses, Vol. 11, Pages 966: Persistent Infection with Herpes Simplex Virus 1 and Alzheimer’s Disease—A Call to Study How Variability in Both Virus and Host may Impact Disease Viruses doi: 10.3390/v11100966 Authors: Colleen A. Mangold Moriah L. Szpara Increasing attention has focused on the contributions of persistent microbial infections with the manifestation of disease later in life, including neurodegenerative conditions such as Alzheimer’s disease (AD). Current data has shown the presence of herpes simplex virus 1 (HSV-1) in regions of the brain that are impacted by AD in elderly indivi...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Publication date: Available online 18 October 2019Source: Molecular and Biochemical ParasitologyAuthor(s): Felicity E. Lumb, Jenny Crowe, James Doonan, Colin J. Suckling, Colin Selman, Margaret M. Harnett, William HarnettAbstractOne of the most rapidly increasing human public health problems is obesity, whose sequelae like type-2 diabetes, represent continuously worsening, life-long conditions. Over the last 15 years, data have begun to emerge from human and more frequently, mouse studies, that support the idea that parasitic worm infection can protect against this condition. We have therefore investigated the potential of...
Source: Molecular and Biochemical Parasitology - Category: Parasitology Source Type: research
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Source: Parasitology International - Category: Parasitology Source Type: research
In conclusion, the present study demonstrates the high seroprevalence of T. gondii in small ruminants in Mongolia. Our results highlight that country-wide control measures are required to minimize infections in livestock.Graphical abstract
Source: Parasitology International - Category: Parasitology Source Type: research
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Source: Ticks and Tick borne Diseases - Category: Zoology Source Type: research
Publication date: Available online 18 October 2019Source: Colloids and Surfaces A: Physicochemical and Engineering AspectsAuthor(s): Amy L. Polaczyk, James E. Amburgey, Amir Alansari, Jordan C. Poler, Marco Propato, Vincent R. HillAbstractThe electrophoretic mobilities (EPM’s) of fifteen different microbes (6 viruses, 5 vegetative bacteria, 2 bacterial endospores, 2 protozoa) and one microbial particle surrogate (Polystyrene microspheres) were measured, and five models were used to convert EPM's of these microorganisms to zeta potentials. The Helmholtz-Smoluchowski, Hückel-Onsager, Henry, modified Booth, and O&r...
Source: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Category: Chemistry Source Type: research
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