Effects of birth months on rheumatic diseases in South Korea: a nationwide case-control study.

CONCLUSIONS: Seasonal variations in infectious agents, sun exposure, and food ingestion during gestation or early infancy seem to explain the association between birth month/season and development of rheumatic diseases. PMID: 31498065 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research

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l;nke G Abstract Mononuclear phagocytes, including monocytes and macrophages, are a central component of the host's innate immune system designated to protect against invading pathogens. However, these cells do not only interact with various parts of the innate and adaptive immune system, but also fulfill indispensable duties during the control of tissue homeostasis and organ function. Moreover, macrophages are crucially involved in tissue remodeling and repair in response to damage. Simultaneously, mononuclear phagocytes might also contribute to the pathogenesis of various inflammatory and autoimmune diseases. In...
Source: Advances in Immunology - Category: Allergy & Immunology Authors: Tags: Adv Immunol Source Type: research
Publication date: Available online 14 October 2019Source: Life SciencesAuthor(s): Gleison Daion Piovezana Bossolani, Bruna Thais Silva, Juliana Vanessa Colombo Martins Perles, Mariana Machado Lima, Flávia Cristina Vieira Frez, Sara Raquel Garcia de Souza, Camila Caviquioli Sehaber-Sierakowski, Ciomar Aparecida Bersani-Amado, Jacqueline Nelisis ZanoniAbstractAimsThe aim of our study was to study the pathological mechanisms induced by the rheumatoid arthritis (RA) on the Enteric Nervous System (ENS).Main methodsWe evaluated the effect of the chronic arthritis and its treatment with 50 mg/kg quercetin alone (AQ) and ...
Source: Life Sciences - Category: Biology Source Type: research
Conclusions: Self-management and rehabilitation of fibromyalgia it is not only about learning to manage the symptoms but also about the struggle to find coherence in life through re-constructing gender identity that is acceptable both for the individual and for the community. PMID: 31607231 [PubMed - in process]
Source: International Journal of Qualitative Studies on Health and Well-being - Category: International Medicine & Public Health Tags: Int J Qual Stud Health Well-being Source Type: research
We describe genetic location and functions of various genetic defect associated with VEO-IBD with their key clinical manifestations. We also provide clinical clues to suspect these conditions and approaches to the diagnosis of these disorders and suitable treatment options.
Source: Genes and Diseases - Category: Genetics & Stem Cells Source Type: research
Macrophages are commonly classified as M1 macrophages or M2 macrophages. The M2 macrophages are further sub-categorized into M2a, M2b, M2c, and M2d subtypes. The M2a, M2b, and M2c subtypes play roles in anti-inflammatory activity, tissue remodeling, type 2 T helper cell (Th2) activation, and immunoregulation. Previous studies have shown that macrophage exosomes can affect some disease processes. Exosomes are 30–150-nm lipid bilayer membrane vesicles derived from most living cells, with important biological functions. The role of exosomes in preventing the development of autoimmune diseases, including inflammatory bow...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Consider applying the Neuman systems model to provide holistic care for more positive outcomes.
Source: Nursing Made Incredibly Easy - Category: Nursing Tags: Feature Source Type: research
ConclusionsThe hypoglycemic mechanism of DOP might be associated with the regulation of glucagon-mediated hepatic glycogen metabolism and gluconeogenesis, and of liver glycogen structure, contributing to improved hepatic glucose metabolism in diabetic mice.Graphical abstractDOP could regulate glucagon-mediated signaling pathways and reverse the instability of liver glycogen structure, contributing to improved hepatic glucose metabolism.
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Boston University researchers found that while effective in treating pain, cortisone jabs can speed up a joint's disintegration and force patients to have full knee or hip replacements.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Authors: Su H, Kang Q, Wang H, Yin H, Duan L, Liu Y, Fan R Abstract [This corrects the article DOI: 10.3892/etm.2019.7253.]. PMID: 31608129 [PubMed - in process]
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
The TV ad promises pain relief for knee osteoarthritis, the source of most of the 600,000 knee replacement surgeries performed in the US each year. A man in a bowling alley winces with pain. He nearly falls as he rolls a ball into the gutter. (Did I mention the arrow sticking out of his knee?) “Knee acting up again?” asks his buddy, clearly concerned. When pain pills don’t seem to help, his buddy suggests a procedure called Coolief for knee osteoarthritis. “I had it done six months ago,” says the bowling buddy. “And the best part is that it lasts up to one year.” What is Coolief? C...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Arthritis Bones and joints Osteoarthritis Pain Management Tests and procedures Source Type: blogs
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