PET/MRI may help diagnose fevers of unknown origin
PET/MRI imaging shows promise in diagnosing fevers or inflammation of unknown origin and may have advantages over PET/CT, according to a study published January 3 in the European Journal of Radiology.In a study that included 104 patients, PET/MRI provided high sensitivity and specificity for determining underlying causes, especially in patients with elevated C-reactive protein, a blood biomarker of inflammation, according to lead author Tomas Rohan, MD, of University Hospital Brno in Brno, Czechia.“To make the indications more specific to and improve the overall diagnostic performance, F-18 FDG-PET/MRI should be indicate...
Source: AuntMinnie.com Headlines - January 8, 2024 Category: Radiology Authors: Will Morton Tags: Molecular Imaging Source Type: news

Sarilumab Beneficial for Polymyalgia Rheumatica Patients
THURSDAY, Oct. 5, 2023 -- For patients with polymyalgia rheumatica with relapse during tapering of glucocorticoid therapy, treatment with sarilumab, the human monoclonal antibody that binds to the interleukin-6 receptorα, is efficacious for... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - October 5, 2023 Category: Pharmaceuticals Source Type: news

Everything (Maybe) You Wanted to Know About Sarilumab for PMR
(MedPage Today) -- Clinicians and others curious about the data underlying February's FDA approval of sarilumab (Kevzara) for polymyalgia rheumatica (PMR) can now be sated, at least partially, with publication today of the chief registration trial... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - October 5, 2023 Category: Rheumatology Source Type: news

JAK Signaling May Be Behind Polymyalgia Rheumatica
MONDAY, July 10, 2023 -- Janus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study published online June 29 in PLOS... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 10, 2023 Category: Pharmaceuticals Source Type: news

Polymyalgia Rheumatica Presenting As Sternoclavicular Arthritis Polymyalgia Rheumatica Presenting As Sternoclavicular Arthritis
This patient presented with atypical manifestations of polymyalgia rheumatica and giant cell arteritis. How was it diagnosed?Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 3, 2023 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

FDA Approves First Biologic Treatment for Polymyalgia Rheumatica FDA Approves First Biologic Treatment for Polymyalgia Rheumatica
The interleukin-6 receptor antagonist sarilumab (Kevzara) will be indicated in adults who have had an inadequate response to corticosteroids or could not tolerate a corticosteroid taper.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - March 1, 2023 Category: Drugs & Pharmacology Tags: Rheumatology News Alert Source Type: news

Kevzara (sarilumab) Approved by FDA as First and Only Biologic Indicated for Patients with Polymyalgia Rheumatica
Cambridge, MA and Tarrytown, N.Y. February 28, 2023. The U.S. Food and Drug Administration (FDA) has approved Kevzara® (sarilumab) for the treatment of polymyalgia rheumatica (PMR), an inflammatory rheumatic disease, in adult patients who have... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - February 28, 2023 Category: Drugs & Pharmacology Source Type: news

JAK Inhibitor Promising for Polymyalgia Rheumatica
(MedPage Today) -- Tofacitinib (Xeljanz) appeared highly effective against polymyalgia rheumatica (PMR) in a small single-arm trial, researchers said, suggesting another potential alternative to long-term corticosteroids. Among 14 patients in... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - January 9, 2023 Category: Rheumatology Source Type: news

Sarilumab Effective for Polymyalgia Rheumatica in Phase 3 Trial Sarilumab Effective for Polymyalgia Rheumatica in Phase 3 Trial
Relapsing patients treated with the biologic had significantly higher sustained remission and reported better quality of life, compared with the control group, in a randomized controlled trial.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - November 22, 2022 Category: Drugs & Pharmacology Tags: Rheumatology News Source Type: news

Is PMR the Next Indication for Tocilizumab?
(MedPage Today) -- About half of patients with steroid-dependent polymyalgia rheumatica (PMR) were able to get off steroids altogether when they were started on tocilizumab (Actemra) infusions, which also improved disease control in most cases... (Source: MedPage Today Rheumatology)
Source: MedPage Today Rheumatology - September 20, 2022 Category: Rheumatology Source Type: news

Rheumatoid Arthritis vs. Polymyalgia Rheumatica
Title: Rheumatoid Arthritis vs. Polymyalgia RheumaticaCategory: Diseases and ConditionsCreated: 3/4/2022 12:00:00 AMLast Editorial Review: 3/4/2022 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - March 4, 2022 Category: Rheumatology Source Type: news

What Triggers Polymyalgia Rheumatica
? (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 6, 2020 Category: General Medicine Source Type: news

Getting the Right Care for Painful Autoimmune Conditions
A corticosteroid can quickly relieve symptoms of both polymyalgia rheumatica and temporal arteritis. But a delay could cause vision loss, a stroke or even death. (Source: NYT Health)
Source: NYT Health - August 19, 2019 Category: Consumer Health News Authors: Jane E. Brody Tags: Stroke Steroids Autoimmune Diseases Immune System Source Type: news

Oral Steroids Increase Infection Risk in Inflammatory Disease
MONDAY, June 24, 2019 -- The incidence of infection increases with glucocorticoid dose for patients with polymyalgia rheumatica or giant cell arteritis, according to a study published online June 24 in CMAJ, the journal of the Canadian Medical... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 24, 2019 Category: Pharmaceuticals Source Type: news

Oral steroids put patients with inflammatory disease at high risk of infection
(Joule Inc.) Oral steroid use in patients with the inflammatory diseases polymyalgia rheumatica and/or giant cell arteritis significantly increased the risk of infection, and the risk increased with higher doses, found a study in CMAJ (Canadian Medical Association Journal). (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 24, 2019 Category: International Medicine & Public Health Source Type: news