What Was the Cause of the Excruciating Pain in His Shoulders and Hips? - The New York Times
As the physician prepared to leave the exam room, the patient's wife spoke up:"Doctor, my husband won't tell you this, but he is suffering," the woman said, her voice cracking. Dr. Timothy Quan, a rheumatologist in central Connecticut, looked at the 69-year-old man he'd been caring for over the past several months. The man gave a brisk nod. It was true. The past few weeks had been a nightmare of pain.Six months earlier, the patient woke up with a sore, swollen right hand. He figured he must have injured it a few days before when he cleared out a pile of wood in his backyard. He mentioned it to his pri...
Source: Psychology of Pain - June 5, 2019 Category: Anesthesiology Source Type: blogs

The Wheat Belly Timeline: The First Few Weeks
With all our talk of opiate withdrawal syndromes accompanied by nausea, headache, fatigue, and depression, it can be daunting, even terrifying, to people who face the prospect of tossing all wheat and grains into the trash bin, vowing to never let a Danish, donut, or dish of pasta cross your lips again. So it may help to lay out a timeline of what and when various changes can develop in the Wheat Belly wheat- and grain-free lifestyle. You can expect different symptoms and health conditions to recede at different rates, since they are caused by a variety of different mechanisms. For instance, the direct gastrointestinal tox...
Source: Wheat Belly Blog - October 26, 2018 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle acid reflux detoxification grains IBS Inflammation joint pain opiates withdrawal Source Type: blogs

The suffering man resolved
This article  Polymyalgia rheumatica vs late-onset rheumatoid arthritis   adds some confusion to my previous conclusions. This abstract continues my confusion – Presenting features of polymyalgia rheumatica (PMR) and rheumatoid arthritis with PMR-like onset: a prospective study So I am not sure about the final diagnosis because he definitely had characteristics of both.  The good news is that both respond to low dose prednisone.   (Source: DB's Medical Rants)
Source: DB's Medical Rants - September 27, 2018 Category: Internal Medicine Authors: rcentor Tags: Medical Rants Source Type: blogs

Leucovorin to the Rescue​
A 78-year-old man was advised to go to the emergency department by his rheumatologist after reporting symptoms of nausea, severe fatigue, and feeling "off" for two days. The patient had recently been prescribed methotrexate for his polymyalgia rheumatica, and was instructed to take 5 mg once a week, but he misunderstood and took 5 mg daily for six days.The patient's heart rate was 80 beats per minute, his blood pressure was 155/75 mm Hg, his pulse ox was 98% on room air, and his temperature was 98°F. His initial labs included a CBC with no abnormalities, but his creatinine was 2.5 mg/dL with a GFR of 25. Baselin...
Source: The Tox Cave - August 1, 2016 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Wheat Belly: Self-Directed Health?
Director chair, film slate and load horn. Here’s a proposal for you: If, by following the Wheat Belly lifestyle, a long list of conditions are reduced or reversed at no risk, almost no cost, reversing even chronic and potentially fatal conditions . . . does that mean that the notion of self-directed health might be on the horizon, i.e., putting control over health back in our own hands? I think it does. No, we will never implant our own defibrillators or take out our own gallbladders. But so many chronic health conditions afflicting modern humans recede that I believe that it is entirely reasonable to start talking a...
Source: Wheat Belly Blog - February 16, 2016 Category: Cardiology Authors: Dr. Davis Tags: Wheat Belly Lifestyle arthritis autoimmune diabetes eating disorder gluten grains Inflammation joint Weight Loss Source Type: blogs

Gliadin: The Universal Human Poison
Autoimmunity is the process describing an immune response waged against our own organs. The complex collection of mechanisms consisting of T and B lymphocytes, antibodies, and others, meant to provide protection against viruses, bacteria, and other body invaders, is misdirected against proteins of the body’s organs, such as liver, pancreas, thyroid, or brain. Autoimmune conditions now affect 8% of the American population–it is increasingly looking like diseases of autoimmunity are out of control. Dr Alessio Fasano was recently awarded the Linus Pauling Award, the highest award from the Institute for Functional...
Source: Wheat Belly Blog - October 7, 2013 Category: Cardiology Authors: Dr. Davis Tags: Autoimmunity Gliadin Source Type: blogs

How quickly does wheatlessness unfold?
Wheatlessness: the happy, healthy state achieved by not eating wheat. A frequently asked question: Once you eliminate wheat, how fast do the benefits occur? Well, it depends. It depends on what health issue we are discussing, what organ system, and how far along the process of wheat destruction you were. Nonetheless, there are a number of common patterns that develop once you decide to eliminate all things wheat in your life: Gastrointestinal Acid reflux, bowel urgency–5 days is typical for these conditions to reduce or go away entirely. Ulcerative colitis, Crohns–These complex inflammatory conditions require...
Source: Wheat Belly Blog - June 14, 2013 Category: Cardiology Authors: Dr. Davis Tags: Wheat-ectomy Wheat-elimination success stories Source Type: blogs