Rheumatology: What You May Have Missed in 2023
Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0678. Online ahead of print.ABSTRACTMany patients with rheumatologic conditions receive care from physicians other than rheumatologists. Here we note key findings from 6 studies in rheumatology published in 2023 that offer valuable insights for internal medicine specialists and subspecialists outside of rheumatology. The first study investigated the effect of low-dose glucocorticoids on patients with rheumatoid arthritis (RA) over 2 years and challenged existing perceptions about the risks of glucocorticoids in this setting. The second study focused on the updated guideline for...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Kafaf Jalali Lisa A Mandl Source Type: research
Rheumatology: What You May Have Missed in 2023
Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0678. Online ahead of print.ABSTRACTMany patients with rheumatologic conditions receive care from physicians other than rheumatologists. Here we note key findings from 6 studies in rheumatology published in 2023 that offer valuable insights for internal medicine specialists and subspecialists outside of rheumatology. The first study investigated the effect of low-dose glucocorticoids on patients with rheumatoid arthritis (RA) over 2 years and challenged existing perceptions about the risks of glucocorticoids in this setting. The second study focused on the updated guideline for...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Kafaf Jalali Lisa A Mandl Source Type: research
Rheumatology: What You May Have Missed in 2023
Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0678. Online ahead of print.ABSTRACTMany patients with rheumatologic conditions receive care from physicians other than rheumatologists. Here we note key findings from 6 studies in rheumatology published in 2023 that offer valuable insights for internal medicine specialists and subspecialists outside of rheumatology. The first study investigated the effect of low-dose glucocorticoids on patients with rheumatoid arthritis (RA) over 2 years and challenged existing perceptions about the risks of glucocorticoids in this setting. The second study focused on the updated guideline for...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Kafaf Jalali Lisa A Mandl Source Type: research
Rheumatology: What You May Have Missed in 2023
Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0678. Online ahead of print.ABSTRACTMany patients with rheumatologic conditions receive care from physicians other than rheumatologists. Here we note key findings from 6 studies in rheumatology published in 2023 that offer valuable insights for internal medicine specialists and subspecialists outside of rheumatology. The first study investigated the effect of low-dose glucocorticoids on patients with rheumatoid arthritis (RA) over 2 years and challenged existing perceptions about the risks of glucocorticoids in this setting. The second study focused on the updated guideline for...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Kafaf Jalali Lisa A Mandl Source Type: research
Polymyalgia Rheumatica After COVID-19 Vaccination: Data from the EudraVigilance Database
Acta Med Port. 2024 Apr 12. doi: 10.20344/amp.20952. Online ahead of print.NO ABSTRACTPMID:38607657 | DOI:10.20344/amp.20952 (Source: Acta Medica Portuguesa)
Source: Acta Medica Portuguesa - April 12, 2024 Category: General Medicine Authors: Cl áudia Pinto Oliveira Sofia Ferreira Azevedo Carolina Vilafanha Ana Rita Prata Anabela Barcelos Source Type: research
Immune checkpoints in autoimmune vasculitis
Best Pract Res Clin Rheumatol. 2024 Apr 9:101943. doi: 10.1016/j.berh.2024.101943. Online ahead of print.ABSTRACTGiant cell arteritis (GCA) is a prototypic autoimmune disease with a highly selective tissue tropism for medium and large arteries. Extravascular GCA manifests with intense systemic inflammation and polymyalgia rheumatica; vascular GCA results in vessel wall damage and stenosis, causing tissue ischemia. Typical granulomatous infiltrates in affected arteries are composed of CD4+ T cells and hyperactivated macrophages, signifying the involvement of the innate and adaptive immune system. Lesional CD4+ T cells under...
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Yuki Sato Maria Tada Jorg J Goronzy Cornelia M Weyand Source Type: research
The effect of prednisolone and a short-term prednisolone discontinuation for the diagnostic accuracy of FDG-PET/CT in polymyalgia rheumatica-a prospective study of 101 patients
CONCLUSION: FDG-PET/CT has limited diagnostic accuracy for differentiating PMR from other inflammatory diseases. If FDG-PET/CT is intended for diagnostic purposes, prednisolone should be discontinued to enhance diagnostic accuracy.TRIAL REGISTRATION: ClinicalTrials.gov (NCT04519580). Registered 17th of August 2020.PMID:38563881 | DOI:10.1007/s00259-024-06697-8 (Source: Molecular Medicine)
Source: Molecular Medicine - April 2, 2024 Category: Molecular Biology Authors: Andreas Wiggers Nielsen Ib T ønder Hansen Berit Dalsgaard Nielsen S øren Geill Kjær Jesper Blegvad-Nissen Kate Rewers Christian M øller Sørensen Ellen-Margrethe Hauge Lars Christian Gormsen Kresten Krarup Keller Source Type: research
The effect of prednisolone and a short-term prednisolone discontinuation for the diagnostic accuracy of FDG-PET/CT in polymyalgia rheumatica-a prospective study of 101 patients
CONCLUSION: FDG-PET/CT has limited diagnostic accuracy for differentiating PMR from other inflammatory diseases. If FDG-PET/CT is intended for diagnostic purposes, prednisolone should be discontinued to enhance diagnostic accuracy.TRIAL REGISTRATION: ClinicalTrials.gov (NCT04519580). Registered 17th of August 2020.PMID:38563881 | DOI:10.1007/s00259-024-06697-8 (Source: Molecular Medicine)
Source: Molecular Medicine - April 2, 2024 Category: Molecular Biology Authors: Andreas Wiggers Nielsen Ib T ønder Hansen Berit Dalsgaard Nielsen S øren Geill Kjær Jesper Blegvad-Nissen Kate Rewers Christian M øller Sørensen Ellen-Margrethe Hauge Lars Christian Gormsen Kresten Krarup Keller Source Type: research
The effect of prednisolone and a short-term prednisolone discontinuation for the diagnostic accuracy of FDG-PET/CT in polymyalgia rheumatica —a prospective study of 101 patients
ConclusionFDG-PET/CT has limited diagnostic accuracy for differentiating PMR from other inflammatory diseases. If FDG-PET/CT is intended for diagnostic purposes, prednisolone should be discontinued to enhance diagnostic accuracy.Trial registrationClinicalTrials.gov (NCT04519580). Registered 17th of August 2020. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research
Polymyalgia rheumatica and giant cell arteritis following COVID-19 vaccination: Results from a nationwide survey
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - April 2, 2024 Category: Allergy & Immunology Authors: Pierre-Andr é JarrotAdrien MirouseSébastien OttavianiSimon CadiouJean-Hugues SalmonEric LiozonSimon ParreauMartin MichaudBenjamin TerrierPierre-Edouard GavandLudovic TrefondVirginie LavoiepierreJeremy KeraenDaniel RekassaBastien BouldoiresThierry Weitte Source Type: research
The effect of prednisolone and a short-term prednisolone discontinuation for the diagnostic accuracy of FDG-PET/CT in polymyalgia rheumatica —a prospective study of 101 patients
ConclusionFDG-PET/CT has limited diagnostic accuracy for differentiating PMR from other inflammatory diseases. If FDG-PET/CT is intended for diagnostic purposes, prednisolone should be discontinued to enhance diagnostic accuracy.Trial registrationClinicalTrials.gov (NCT04519580). Registered 17th of August 2020. (Source: European Journal of Nuclear Medicine and Molecular Imaging)
Source: European Journal of Nuclear Medicine and Molecular Imaging - April 2, 2024 Category: Nuclear Medicine Source Type: research
Effectiveness of methotrexate and leflunomide as corticoid-sparing drugs in patients with polymyalgia rheumatica
CONCLUSIONS: This study demonstrated the clinical effectiveness of LEF and even its superiority in achieving remission when compared with MTX as GCSD in PMR patients. Further research is needed to support these findings.PMID:38560643 | PMC:PMC10978571 | DOI:10.1093/rap/rkae033 (Source: Adv Data)
Source: Adv Data - April 1, 2024 Category: Epidemiology Authors: Juan Pablo Vinicki Alejandra Cusa Daniela Domingo Jos é Luis Velasco Zamora Sebasti án Magri Alejandro Brigante Maria Marcela Schmid Paola Ávila Natalia Zamora Laura Sorrentino Anabella M Rodriguez Miguel Linarez Cecilia Pisoni Carolina Costi Gustavo R Source Type: research
Did the first description of patients with polymyalgia rheumatica take place in Scotland or in Denmark?
Reumatismo. 2024 Mar 22;76(1). doi: 10.4081/reumatismo.2024.1673.ABSTRACTThe first description of polymyalgia rheumatica (PMR) is generally attributed to Dr. Bruce. In an 1888 article entitled Senile rheumatic gout, he described five male patients aged from 60 to 74 years whom he had visited at the Strathpeffer spa in Scotland. In 1945, Dr. Holst and Dr. Johansen reported on five female patients examined over several months at the Medical Department of Roskilde County Hospital in Denmark. These patients suffered from hip, upper arms, and neck pain associated with elevated ESR and constitutional manifestations such as low-g...
Source: Reumatismo - March 25, 2024 Category: Rheumatology Authors: C Manzo M Isetta A Castagna Source Type: research
