Association of plasma homocysteine level with vaso-occlusive crisis in sickle cell anemia patients of Odisha, India

AbstractVascular complications of sickle cell anemia (SCA) are influenced by many factors. Elevated plasma homocysteine (Hcy) is supposed to be an independent risk factor and is either genetic or nutritional origin. The present study evaluated the plasma Hcy level, MTHFR C677T gene polymorphism, effect of folic acid (FA) supplementation ‚ and hemato-biochemical parameters in SCA and their effect on the vaso-occlusive crisis (VOC) in SCA patients of an Asian-Indian haplotype population. One hundred twenty cases of SCA (HbSS) and 50 controls with normal hemoglobin(HbAA) were studied. It was found that the plasma Hcy level is signif icantly higher (p 
Source: Annals of Hematology - Category: Hematology Source Type: research

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In conclusion, P. gigas is suggested to feed on indigestible materials such as plants, algae, and sediments, and potentially experience fasting in a reservoir. PMID: 32972085 [PubMed - in process]
Source: Zoological Science - Category: Zoology Authors: Tags: Zoolog Sci Source Type: research
Authors: Ribeiro-Filho J, Yahouédéhou SCMA, Pitanga TN, Santana SS, Adorno EV, Barbosa CG, Ferreira JRD, Pina ETG, Dos Santos Neres JS, Leite IPR, Lyra IM, Goncalves MS Abstract INTRODUCTION: Ticagrelor is an antiplatelet agent approved for the treatment of patients with an acute coronary syndrome or a history of myocardial infarction. Considering the evidence demonstrating that ticagrelor-mediated inhibition of platelet activation and aggregation have beneficial effects in the treatment of thrombotic conditions, clinical studies have been conducted to evaluate the use of this drug for the treatment o...
Source: Expert Review of Hematology - Category: Hematology Tags: Expert Rev Hematol Source Type: research
CONCLUSION: This case highlights that rare vascular alterations such as RAP can develop in subjects with ocular tuberculosis. PMID: 32976040 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
We examined treatment outcomes in PVT and aimed to identify predictors of incomplete recanalization and portal hypertensive complications. MATERIALS AND METHODS: This retrospective study comprised patients diagnosed with PVT between 2006 and 2015. Key exclusion criteria were liver cirrhosis, malignancy, and age
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
Authors: Su Y, Ma M, Zhang H, Pan X, Zhang X, Zhang F, Lv Y, Yan C Abstract Hyponatremia is a risk factor associated with poor prognosis in patients with heart failure (HF) with reduced ejection fraction. However, whether hyponatremia has a similar role in patients with HF with preserved ejection fraction (HFpEF) has remained controversial. Therefore, the present study aimed to investigate the clinical characteristics and 24-month prognostic profile of a cohort of patients with HFpEF in China. From a registered observational cohort study on 1,027 subjects with HF, 496 patients with HFpEF were included. The associat...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
[Monitor] Stakeholders in the fight against Sickle Cell Disease have launched a campaign to raise funds for the establishment of a digital registry of all persons living with Sickle Cell Disease.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
A study offered an explanation for children ’s ability to fight off the virus. The lockdown in Melbourne, Australia, is being further eased.
Source: NYT Health - Category: Consumer Health News Tags: Coronavirus (2019-nCoV) Source Type: news
India has registered 88,600 new confirmed coronavirus cases in the past 24 hours in a declining trend with recoveries exceeding daily infections
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
Authors: Uvais NA, Rasmina V PMID: 32975917 [PubMed - as supplied by publisher]
Source: The Primary Care Companion for CNS Disorders - Category: Primary Care Tags: Prim Care Companion CNS Disord Source Type: research
Publication date: Available online 25 September 2020Source: Meat ScienceAuthor(s): Sri Rahayu Hijrah Hati, Ina Zulianti, Adrian Achyar, Anya Safira
Source: Meat Science - Category: Food Science Source Type: research
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