Non-alcoholic fatty liver disease and hypercholesterolemia: Roles of thyroid hormones, metabolites, and agonists.

Conclusions TH-based therapies show clinical promise for the treatment of NAFLD and hypercholesterolemia. Strategies for limiting side effects of TH are being developed, and may enable TH metabolites and analogues to have specific effects in the liver for treatments of these conditions. These liver-specific effects and potential suppression of the HPT axis raise the issue of monitoring liver-specific markers of TH action in order to assess clinical efficacy and dosing of these compounds. PMID: 31389309 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research