Gomisin M2 Inhibits Mast Cell-Mediated Allergic Inflammation via Attenuation of Fc εRI-Mediated Lyn and Fyn Activation and Intracellular Calcium Levels

In conclusion, G.M2 exhibits anti-allergic effects through suppression of the Lyn and Fyn pathways in mast cells. According to these findings, we suggest that G.M2 has potential as a therapeutic agent for the treatment of allergic inflammatory diseases via suppression of mast cell activation.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research