Safety and efficacy of clonidine on postoperative vomiting and pain in pediatric ophthalmic surgery: a systematic review and meta-analysis.

CONCLUSIONS: Compared to placebo or benzodiazepine, clonidine premedication was effective in reducing postoperative vomiting in pediatric patients undergoing ophthalmic surgery. Clonidine premedication also provided more reduction in postoperative pain when compared to placebo. The use of clonidine premedication was not associated with adverse hemodynamic events. This article is protected by copyright. All rights reserved. PMID: 31343796 [PubMed - as supplied by publisher]
Source: Paediatric Anaesthesia - Category: Anesthesiology Authors: Tags: Paediatr Anaesth Source Type: research