Short-Term Activation of Peroxisome Proliferator-Activated Receptors α and γ Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats.

In conclusion, short-term treatment with PPAR agonists induced tissue-specific effects on FA composition in liver and heart. Moreover, both PPARα and PPARγ activation lowered plasma TAG and phospholipids, most likely through effects on liver and adipose tissue, respectively. In future studies we aim to reveal whether similar patterns can be found through diet-induced activation of specific pathways. PMID: 31308847 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/31308847?dopt=Abstract

Source: PPAR Research - July 18, 2019 Category: Genetics & Stem Cells Tags: PPAR Res Source Type: research