Multifarious Pharmacological Applications of Green Routed Eco-Friendly Iron Nanoparticles Synthesized by Streptomyces Sp. (SRT12).

Multifarious Pharmacological Applications of Green Routed Eco-Friendly Iron Nanoparticles Synthesized by Streptomyces Sp. (SRT12). Biol Trace Elem Res. 2019 Jun 29;: Authors: Rajeswaran S, Somasundaram Thirugnanasambandan S, Dewangan NK, Moorthy RK, Kandasamy S, Vilwanathan R Abstract A simple, eco-friendly, green routine co-precipitation method was experimented to synthesize iron nanoparticles (Fe-NPs) using the cell-free supernatant of actinobacteria. The biosynthesized nanoparticles were characterized by UV-Vis spectroscopy, X-ray diffractometer (XRD), energy-dispersive X-ray (EDX), scanning electron microscopy (SEM), atomic force microscopy (AFM), zeta potential analyser and Fourier transform infrared (FTIR) spectroscopy. The synthesized nanoparticles were crystalline, quasi-spherical in shape and their average size ranged from 65.0 to 86.7 nm. In our radical scavenging assays, the nanoparticles have revealed a strong antioxidant activity with respective standard ascorbic acid. The nanoparticles also exhibited a wide bactericidal action on pathogens namely Bacillus subtilis, Staphylococcus aureus, Klebsiella pneumoniae, Shigella flexneri and Escherichia coli. At 75 μg/ml concentration, the nanoparticles showed the highest inhibition against S. aureus (16.2 ± 0.45 mm), the lowest zone of inhibition was seen against K. pneumoniae (12.3 ± 0.50 mm) and moderate inhibition on other strains. Further, its cytotoxicity was...
Source: Biological Trace Element Research - Category: Biology Authors: Tags: Biol Trace Elem Res Source Type: research