Oral squamous cell carcinoma arising in a patient with Werner syndrome
Werner syndrome (WS) is an autosomal recessive disorder characterized by physical signs and symptoms, including premature aging and scleroderma-like skin changes. The gene responsible for WS is the WRN gene. A significant proportion of WS-related malignant tumours are non-epithelial types, and the incidence of oral squamous cell carcinoma (SCC) is rare. A case of oral SCC of the lower alveolus and gingiva arising in a 63-year-old woman with WS is reported here. Biopsy confirmed moderately differentiated SCC.
Source: International Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: N. Kuribayashi, D. Uchida, Y. Hamasaki, H. Kawamata Tags: Case Report Source Type: research
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