Progressive multifocal leukoencephalopathy in a 27-year-old lady with systemic lupus erythematosus – rheumatoid arthritis overlap syndrome

We report this case to raise the importance of clinical alertness for the rare but possibly underdiagnosed disease.
Source: Journal of the Formosan Medical Association - Category: General Medicine Source Type: research

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We report this case to raise the importance of clinical alertness for the rare but possibly underdiagnosed disease. PMID: 31202498 [PubMed - as supplied by publisher]
Source: J Formos Med Assoc - Category: General Medicine Authors: Tags: J Formos Med Assoc Source Type: research
Conclusion: There is a high prevalence of AID among patients with DLBCL. AIDs categorized as primarily B-cell mediated (in this study mainly RA, systemic lupus erythematosus and Sjögren's syndrome) may be associated with inferior OS. AID patients may be more prone to neutropenic fever compared to patients without concomitant AID. PMID: 31131659 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research
Publication date: Available online 11 May 2019Source: Best Practice &Research Clinical Obstetrics &GynaecologyAuthor(s): Giuseppe Benagiano, Marisa Benagiano, Paola Bianchi, Mario Milco D’Elios, Ivo BrosensAbstractAutoimmune diseases (AIDs) affect women with a 2 - 1 ratio vs. men, suggesting that hormonal contraceptives play a role in their clinical course.Combined oral contraceptives have complex, sometimes contradictory, effects on AIDs; they can worsen the situation in women with Systemic Lupus Erythematosus and with Antiphospholipid Syndrome, condition in which they are contraindicated. Early studies indi...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - Category: OBGYN Source Type: research
CONCLUSION: Our study shows the diagnostic value of auto antibodies in AIDs. It would be interesting to carry out prospective studies on each pathology separately, in order to fill the classic vagaries of the retrospective study and objectively estimate the prevalence in different AIDs. These data on the prevalence of each autoimmune disease are valuable for the public health system. PMID: 30807792 [PubMed - as supplied by publisher]
Source: Human Immunology - Category: Allergy & Immunology Authors: Tags: Hum Immunol Source Type: research
Abstract Autoimmune disease (AID) is a condition in which the immune system breaks down and starts to attack the body. Some common AIDs include rheumatoid arthritis, systemic lupus erythematosus, type 1 diabetes mellitus and so forth. The changes in T-cell receptor (TCR) repertoire have been found in several autoimmune diseases, and may be responsible for the breakdown of peripheral immune tolerance. In this review, we discussed the processes of TCR revision in peripheral immune environment, the changes in TCR repertoire that occurred in various AIDs, and the specifically expanded T cell clones. We hope our discus...
Source: Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Clin Immunol Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In this study, we integrated 5 Cytokine-Chips from genome-wide DNA methylation datasets of the 3 kind of AIDs, delta-beta value was calculated for intergroup difference, and comprehensive bioinformatics analyses of cytokine genes with aberrant methylations were performed. 125 shared differential methylation variabilities (DMVs) were identified. There were 102 shared DMVs with similar methylation status; 3 hypomethylated differential methylation regions (DMRs) across the AIDs were found, and all 3 DMRs were hypomethylated. DMRs (AZU1, LTBR, and RTEL1) were likely to serve as activator in the inflammatory process. Particular...
Source: Journal of Immunology Research - Category: Allergy & Immunology Tags: J Immunol Res Source Type: research
Conclusions CSU patients have an increased risk of AIDs, especially adult female patients with a positive family history and a genetic predisposition for AIDs, who should be screened for signs and symptoms of AIDs.
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
Modern medicine has no cure for autoimmune diseases — and, sadly, most doctors don’t understand them. I’m talking about disorders like rheumatoid arthritis, type 1 diabetes, lupus, fibromyalgia, chronic fatigue syndrome, psoriasis, multiple sclerosis (MS) and more. In all, there are about 80 autoimmune diseases affecting organs throughout the body. They occur when your own immune system becomes overactive and attacks your body instead of diseases and foreign invaders. The standard mainstream treatment for most autoimmune disorders relies on Big Pharma drugs that cover up symptoms or suppress your immun...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Anti-Aging Source Type: news
Conclusion: Our study showed that some IAD are not rare among PLHIV and occur mostly in patients with immuno-virological control under cART. The higher frequency of HCV or hepatitis B virus coinfection for some IAD is also confirmed.
Source: AIDS - Category: Infectious Diseases Tags: Epidemiology and Social Source Type: research
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