PLEK2 promotes gallbladder cancer invasion and metastasis through EGFR/CCL2 pathway.

CONCLUSIONS: On the basis of these collective data, we propose that PLEK2 promotes the invasion and metastasis of GBC by EGFR/CCL2 pathway and PLEK2 can serve as a potential therapeutic target for GBC treatment.
PMID: 31182136 [PubMed - in process]

Source: Cell Research - June 9, 2019 Category: Cytology Authors: Shen H, He M, Lin R, Zhan M, Xu S, Huang X, Xu C, Chen W, Yao Y, Mohan M, Wang J Tags: J Exp Clin Cancer Res Source Type: research