The applicability of multiparameter flow cytometry for the detection of minimal residual disease using different-from-normal panels to predict relapse in patients with acute myeloid leukemia after allogeneic transplantation.

CONCLUSIONS: The assessment of MRD using our self-built different-from-normal AML-MRD detection panel exhibited reliable sensitivity, specificity, and accuracy. In addition, patients with a positive MRD status before transplantation may have higher risk of relapse and worse survival.
PMID: 31162830 [PubMed - as supplied by publisher]

Source: International Journal of Laboratory Hematology - June 3, 2019 Category: Hematology Authors: Wang Z, Guo M, Zhang Y, Xu S, Cheng H, Wu J, Zhang W, Hu X, Yang J, Wang J, Tang G Tags: Int J Lab Hematol Source Type: research