Macrophage tracking near surgically implanted meshes via immunoPET in syngeneic murine models.

In conclusion, we have demonstrated PET imaging of CD11b+ macrophage recruitment to an implanted surgical mesh utilizing pre-clinical PET with a Zr-89-anti-CD11b Mab. ImmunoPET quantification of CD11b levels is a promising approach for inflammation imaging of surgical mesh implants.

Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Nigam, S., Nolfi, A., Stahl, E., Skillen, C., Popovic, B., Brown, B. N., Edwards, W. B. Tags: Preclinical Probes for Cardiovascular Posters Source Type: research