Correlation between metabolic parameters on dual-time-point FDG PET and tumor immune microenvironment marker in non-small cell lung cancer

Conclusions: Hypermetabolic changes on DTP 18F-FDG PET showed good correlation with tumor positive expression of PD-L1 and high density of CD8 TILs and PD-1 in tumor immune microenvironment. Furthermore, dSUVmax was an independent predictor of PD-L1 expression in pretreated NSCLC.

Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Zhou, J., Zou, S., Kuang, D., Cheng, S., Li, D., Chen, L., Zhu, X. Tags: Lung Cancer I: Molecular Biomarkers and Molecular Imaging Signatures Source Type: research