Risks of Cognitive Detriments after Low Dose Heavy Ion and Proton Exposures.

Conclusions: A large number of mouse and rat cognitive testing measures have been reported for a variety of particle species and energies for acute doses. However tissue reactions occur above dose thresholds and very few studies were performed at the heavy ion doses to be encountered on space missions (
Source: International Journal of Radiation Biology - Category: Radiology Tags: Int J Radiat Biol Source Type: research

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What is a CT Scan? A machine whirs in an arc around a patient, snapping a rapid-fire series of x-rays from different angles. These x-ray snapshots are combined by a computer to produce virtual cross-section images of the body. These are called CT scans, which stands for computed tomography (computer-generated cross-sectional images). CT Scans Compared to Ultrasounds and MRIs When the CT scan was first introduced in the 1970s it caused something of a revolution in medicine, allowing doctors to see the inner structure of the body in a way that had been previously hidden – without surgery. Parents often wonder which is ...
Source: Conversations with Dr Greene - Category: Child Development Authors: Tags: Dr. Greene's Blog CT Scan Safety Top Children's Safety Source Type: blogs
In this study, we reviewed major human studies on the health risks of radiation exposure and showed that sex-related factors may potentially influence the long-term response to radiation exposure. Available data suggest that long-term radiosensitivity in women is higher than that in men who receive a comparable dose of radiation. The report on the biological effects of ionizing radiation (BEIR VII) published in 2006 by the National Academy of Sciences, United States emphasized that women may be at significantly greater risk of suffering and dying from radiation-induced cancer than men exposed to the same dose of radiation....
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
Alla S. Koltsova1,2, Anna A. Pendina1, Olga A. Efimova1*, Olga G. Chiryaeva1, Tatyana V. Kuznetzova1 and Vladislav S. Baranov1,2 1D.O. Ott Research Institute of Obstetrics, Gynecology and Reproductology, Saint Petersburg, Russia 2Department of Genetics and Biotechnology, Saint Petersburg State University, Saint Petersburg, Russia In the present review, we focus on the phenomenon of chromothripsis, a new type of complex chromosomal rearrangements. We discuss the challenges of chromothripsis detection and its distinction from other chromoanagenesis events. Along with already known causes and mechanisms, we introdu...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research
In conclusion, potential biological applications of PF-SeNPs were explored by antibacterial, antifungal, antioxidant and biocompatibility assays. Materials and Methods Chemicals and Reagents Sodium selenite (98%), 2,2-diphenyl-1-picrylhydrazyl (DPPH), 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) (MTT), Tween 80, methanol, acetate buffer, tetracycline, nystatin, rhodamine 123, caspase-3 kit, Dulbecco’s modified Eagle media (DMEM), Folin-Ciocalteu reagent, 2,2-azinobis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS), Dulbecco’s phosphate buffered saline pH 7.4 (DPBS) and fetal bovine serum (FBS) w...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusion: This study suggests that a clinically efficacious cardiovascular Chinese herbal medicine (DLP) can be successfully repurposed to treat a lung disease in pulmonary fibrosis guided by TCM theory. Our comparative study between DLP and DHP demonstrated a critical requirement of suppressing both pro-inflammatory and pro-fibrotic pathways for the treatment of pulmonary fibrosis, supporting that a multi-component prescription capable of “removing both phlegm and blood stasis” will better achieve co-protection of heart and lung in PHD. Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic an...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Katarina Rejlekova1, Maria C. Cursano2, Ugo De Giorgi3 and Michal Mego1* 12nd Department of Oncology, Faculty of Medicine, National Cancer Institute, Comenius University, Bratislava, Slovakia 2Oncology Unit, Università Campus Bio-Medico, Rome, Italy 3Medical Oncology Department, Instituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, IRCCS, Meldola, Italy Testicular germ cell tumors (TGCTs) represent the most common solid tumor in young men and is a model of curable cancer. The effectiveness of cisplatin-based chemotherapy secures more than 95% of patients' 5-years survival rate. Howeve...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
“an adult’s perceptions of how the heart has been affected by damage and blockages following a heart attack” – from Broadbent et al 2018 / 2004 By Christian Jarrett Asking patients to draw the parts of their body affected by illness (and similar drawing challenges) can provide insights into how they think about their illness, the seriousness of their condition, and how well they are likely to cope, among other things. For instance, when people who had experienced a heart attack were asked on repeated occasions to draw their heart, an increase in the size of their drawings over time correlated with m...
Source: BPS RESEARCH DIGEST - Category: Psychiatry & Psychology Authors: Tags: Health Source Type: blogs
Conclusion: Use of X + H + T combination therapy significantly increased cell death and possibly improved the treatment. This suggests that the synergistic effect of different therapeutic methods increased cell death in glioblastoma tumor cells and reduced the necessary dose of radiation in the treatment of tumor in radiation therapy.
Source: Journal of Cancer Research and Therapeutics - Category: Cancer & Oncology Authors: Source Type: research
Publication date: Available online 31 October 2018Source: Radiation Physics and ChemistryAuthor(s): Eslam Taha, Fathi Djouider, Essam BanoqitahAbstractThe use of silver nanoparticles as adjuvants in cancer radiation therapy is becoming progressively well acknowledged. Based on simulation methods, we report outcomes on dose enhancement for different silver concentrations implant and different beam energies, using GATE Monte-Carlo simulation. A digital phantom of the head was imported into GATE to provide accurate geometrical representation of the brain tissues. A 1-cm radius spherical tumor was placed at the center of the p...
Source: Radiation Physics and Chemistry - Category: Physics Source Type: research
If self-care steps for back pain such as gentle activity, local heat, or massage don’t ease discomfort within a few weeks to a month, or if you struggle with chronic low back pain, a physiatrist can help you navigate the dizzying number of treatment options. These range from conservative therapies (such as medicines, physical therapy, and chiropractic care) to more invasive options (such as spine injections and spinal surgery). What is a physiatrist? Physiatrists are medical doctors who specialize in physical medicine and rehabilitation. We focus on holistic, nonsurgical care aimed at improving function for people wh...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Back Pain Bones and joints Health Pain Management Source Type: blogs
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