Lipase and factor V (but not viral load) are prognostic factors for the evolution of severe yellow fever cases.

CONCLUSIONS: YF acute severe cases show a generalised involvement of different organs (liver, spleen, heart, kidneys, intestines and pancreas), and different parameters were related to outcome. Factor V and lipase are independent variables associated with death, reinforcing the importance of hemorrhagic events due to fulminant liver failure and pointing to pancreatitis as a relevant event in the outcome of the disease.
PMID: 31116245 [PubMed - in process]

Source: Memorias do Instituto Oswaldo Cruz - May 24, 2019 Category: Infectious Diseases Authors: Casadio LVB, Salles APM, Malta FM, Leite GF, Ho YL, Gomes-Gouvêa MS, Malbouisson LMS, Levin AS, de Azevedo Neto RS, Carrilho FJ, Nastri ACSS, Pinho JRR Tags: Mem Inst Oswaldo Cruz Source Type: research