BDNF and serum S100B levels according the spectrum of structural pathology in chronic pain patients

This study supports the hypothesis that BDNF and S100B neuromodulators present different serum levels according to the background disease associated to the chronic pain. These have the potential to be studied as markers of active disease or treatment evolution.
Source: Neuroscience Letters - Category: Neuroscience Source Type: research

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ConclusionsVitamin D insufficiency was prevalent in both newly diagnosed axSpA patients and healthy controls. There was no association between vitamin D and pain and disease activity in the newly diagnosed axSpA patients. Monitoring vitamin D levels is important and early intervention for vitamin D insufficiency is needed, especially in female patients.
Source: International Journal of Nursing Sciences - Category: Nursing Source Type: research
Publication date: Available online 13 December 2019Source: Brain, Behavior, and ImmunityAuthor(s): N.B. Teixeira, M.B. Sant'Anna, A.C. Giardini, L.P. Araujo, L.A. Fonseca, A.S. Basso, Y. Cury, G. PicoloAbstractMultiple sclerosis (MS) is a Central Nervous System inflammatory demyelinating disease that has as primary symptoms losses of sensory and motor functions, including chronic pain. To date, however, few studies have investigated the mechanisms of chronic pain in animal models of MS since locomotor impairments render difficult its evaluation. It was previously demonstrated that in the MOG35-55-induced EAE, an animal mod...
Source: Brain, Behavior, and Immunity - Category: Neurology Source Type: research
Publication date: Available online 12 December 2019Source: The LancetAuthor(s): Christopher C Butler, Alike W van der Velden, Emily Bongard, Benjamin R Saville, Jane Holmes, Samuel Coenen, Johanna Cook, Nick A Francis, Roger J Lewis, Maciek Godycki-Cwirko, Carl Llor, Sławomir Chlabicz, Christos Lionis, Bohumil Seifert, Pär-Daniel Sundvall, Annelies Colliers, Rune Aabenhus, Lars Bjerrum, Nicolay Jonassen Harbin, Morten LindbækSummaryBackgroundAntivirals are infrequently prescribed in European primary care for influenza-like illness, mostly because of perceived ineffectiveness in real world primary care and becau...
Source: The Lancet - Category: General Medicine Source Type: research
Mass abuse of the drug tramadol spans continents, from India to Africa to the Middle East. The problem is that advocates claimed it was a safer opioid, relieving pain with little risk of abuse
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
St. Vincent Healthcare, Billings MT, Sheila White, acetaminophen, hydrocodone, steal opioids, addiction, tampering,
Source: Office of Criminal Investigations (OCI) Press Releases - Category: Medical Law Authors: Source Type: news
Publication date: Available online 12 December 2019Source: Pharmacological ResearchAuthor(s): Ziqian Cheng, Ranji Cui, Tongtong Ge, Wei Yang, Bingjin LiAbstractOptogenetics is a biological technique, which involves controlling the biological functions of target cells using light. In recent years, optogenetics has become one of the most advanced experimental techniques in neuroscience. It provides precise control on target cells in addition to rapidly and specifically altering the neuronal activity both in vivo and ex vivo. The emergence of optogenetic technology enabled researchers to study the pathogenesis of diseases at ...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
ConclusionThe results support that EO ‘aromatherapy’ can promote dose-dependent regulation of anxiety, depression and OSI and that efficacy requires optimization of dose.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
(CNN/CBS) — At least 1,300 people have died from the flu so far this season, according to a preliminary estimate released Friday by the US Centers for Disease Control and Prevention. There have been at least 2.6 million flu illnesses and 23,000 flu-related hospitalizations, according to the analysis. So far this season, the CDC has received reports of 10 children who have died from the flu, four more than the week before. Experts have warned that flu is hitting the United States early this year, and there are concerns that this early season could mean a particularly severe season overall. Flu spread significantly in ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Flu Source Type: news
(Reuters Health) - While army suicides have historically decreased during wartime, that trend appears to have reversed in recent decades, a new study of U.S. records finds.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
We report a young 22-year-old female with unknown etiology of a pseudoaneurysm, who was previously managed as a psychiatric case and for musculoskeletal pain. On subsequent investigation and confirmation with cardiac magnetic resonance imaging, aneurysmectomy was done. This is a rare case in a young 22-year-old woman with a ventricular pseudoaneurysm of unknown etiology. Considering the high risk for rupture of a ventricular pseudoaneurysm, surgical resection was mandatory with no complications intra- and postprocedure.
Source: Journal of the Saudi Heart Association - Category: Cardiology Source Type: research
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