Infant Exposure to Maternal Depression Affects Later Brain Development, Study Shows

Exposure to maternal depression during the first months of life may have a lasting negative impact on brain development, suggests astudy published Monday inAJP in Advance.“These findings suggest that the perinatal period, particularly the postnatal period, may be critical for prevention of maternal depressive symptoms in view of the long-term association with child brain development,” wrote Runyu Zou, B.Med., M.P.H., of Erasmus Medical College, the Netherlands, a nd colleagues.The study included a total of 3,469 mother-child pairs who participated in the Generation R Study, a Dutch population-based study. Zou and colleagues measured maternal depression using the Brief Symptom Inventory (BSI), a validated self-report questionnaire, at four periods —during pregnancy (approximately 20 weeks' gestation), postpartum (child age 2 months), early childhood (age 3 years), and preadolescence (age 10 years).The researchers measured the children ’s brain development at age 10 using magnetic resonance imaging (MRI); emotional and behavioral problems also were measured at age 10 using the Brief Problem Monitor.Higher maternal depressive symptom scores at all four time points were associated with smaller total gray matter volume in children at age 10. However, after adjusting for possible confounding factors, only exposure to maternal depressive symptoms when the child was 2 months old remained significant. Specifically, a one-point increase on the BSI depressive sym...
Source: Psychiatr News - Category: Psychiatry Tags: ajp in advance child brain development maternal depression MRI perinatal period prevention reduced grey matter two year's old Source Type: research

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Abstract This randomized controlled trial was conducted on 80 Iranian pregnant women with unplanned pregnancy. The participants were randomly assigned to two groups of intervention and control. The intervention group received one to three sessions of individual counseling and six sessions of group counseling each week in six consecutive weeks, and the control group received routine care. The Edinburgh Postnatal Depression Scale and the Spielberger State-Trait Anxiety Inventory were completed by the participants before and 4 weeks after the intervention. There was no significant difference between groups in te...
Source: Community Mental Health Journal - Category: Psychiatry Authors: Tags: Community Ment Health J Source Type: research
I’ve been a mental health therapist for over 10 years and in the social work profession for more than 20. I have been pregnant 8 times, with 4 living children. I consider myself to be pretty self-aware, intelligent, and inquisitive. And yet… I had some form of perinatal mood and anxiety disorders (PMADs) with each of my pregnancies. I just didn’t know it. Oh, sure, I got sad and I got angry and with my older son, I couldn’t let myself fully bond to him until he was 9 months old, but I was fine, right? I even took medication, but that’s normal, right? I was introduced to PMADs last year when ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Parenting Personal Pregnancy Women's Issues Birth trauma perinatal anxiety disorder perinatal mood disorder Postpartum Disorder Source Type: blogs
Objective The aim of the study was to investigate whether symptoms of depression or state anxiety changed the strength or nature of the association between hypertensive disorders of pregnancy (HDP) and gestational age at birth. Methods We conducted a secondary analysis of data from the All Our Families Cohort, a prospective pregnancy cohort study based in Calgary, Alberta, Canada. Self-reported depressive symptoms and state anxiety were assessed between 3 and 5 months of gestation, and obstetrical information, including diagnosis of HDP, parity, type of delivery, and gestational age at birth, was retrieved from the ma...
Source: Psychosomatic Medicine - Category: Psychiatry & Psychology Tags: ORIGINAL ARTICLES Source Type: research
CONCLUSION: Awareness of postnatal depression appeared high. However, areas including anxiety, antenatal mental health, and men's mental health were less well-understood. There remains considerable scope, and a need for, continued awareness-raising around anxiety, mental health in pregnancy and men's mental health. PMID: 31148499 [PubMed - as supplied by publisher]
Source: The International Journal of Social Psychiatry - Category: Psychiatry Authors: Tags: Int J Soc Psychiatry Source Type: research
ConclusionIn this study, postpartum depressive and anxiety symptoms played an important role in shaping difficult infant temperament. Comorbidity between the two conditions warrants clinical attention and additional research, since it is related to maternal perception of difficult infant temperament. Psychological interventions are required, since these women may require assistance with emotional adaptation in the transition to motherhood.
Source: Sexual and Reproductive Healthcare - Category: Reproduction Medicine Source Type: research
In this study, twenty-eight pregnant Wistar rats were divided into four groups and received three-times repeated intraperitoneal injections of normal saline, chrysotile, ascorbic acid and the combination of chrysotile and ascorbic acid on gestational days 11, 14 and 17. The maternal serum levels of malondialdehyde (MDA) and prooxidant-antioxidant balance (PAB) and hippocampal MDA content in adult male offspring were measured. At postnatal day (PND) 60, elevated plus maze was performed to determine anxiety-like behavior, also depression-like behavior was examined using a forced swim test at PND 61- 62. Thereafter, the perce...
Source: Behavioural Brain Research - Category: Neurology Authors: Tags: Behav Brain Res Source Type: research
Conclusions The gestational period is an opportunity to promote positive health behaviors that can have both short- and long-term benefits for the mother. Given the low prevalence of physical activity in young women in general, and the high prevalence of obesity and cardiometabolic diseases among the U.S. population, the public health importance of increasing physical activity in women of childbearing age before, during, and after pregnancy is substantial.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: SPECIAL COMMUNICATIONS Source Type: research
Prior investigations into the relationship between progesterone metabolites and postpartum depression (PPD) have yielded mixed results. We sought to determine the relationship between allopregnanolone during pregnancy and postpartum and concurrent or future symptoms of depression.
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: SYMPOSIUM Source Type: research
AbstractWe investigated the relationship between maternal history of nightshift work before and shift work during pregnancy and offspring risk of depression and anxiety, among mothers participating in the Nurses Health Study II and in their offspring enrolled in the Growing Up Today Study 2 between 2004 and 2013. Case definitions were based on offspring self-reports of physician/clinician-diagnosed depression and/or anxiety, regular antidepressant use and depressive symptoms assessed using the Center for Epidemiologic Studies Depression Scale. Multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were...
Source: European Journal of Epidemiology - Category: Epidemiology Source Type: research
You recently had a baby, and everyone keeps saying that you must be in sheer and utter bliss. Clearly, you’re captivated by your bundle of joy. You must be enamored and in absolute love. I bet you’re just walking on cloud nine. You finally have what you’ve always wanted. Life is complete now, isn’t it? you hear. And all you want to do is cry (or scream) in their face. Because that’s not how you feel. And those aren’t the thoughts running through your mind. Instead, you keep thinking that you’ve made a mistake. A horrible mistake. I never should’ve had this baby. Or you think...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Books General Inspiration & Hope Mental Health and Wellness Parenting Self-Help Women's Issues Source Type: blogs
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