Implementation of a stewardship initiative on respiratory viral PCR ‐based antibiotic de‐escalation

ConclusionA third of patients receiving broad ‐spectrum antibiotics with a positive RV PCR had an opportunity for antimicrobial optimization, although this did not translate into a significant impact on the time to antibiotic de‐escalation or overall antibiotic use. Combination of RV PCR results with biomarkers to rule out bacterial co‐in fections and chest radiographic findings may help enhance the likelihood of accepted antibiotic de‐escalation recommendations and represents an area of future research.This article is protected by copyright. All rights reserved.

Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - May 1, 2019 Category: Drugs & Pharmacology Authors: Pavithra Srinivas, Kaitlyn R. Rivard, Andrea M. Pallotta, Vasilios Athans, Kristin Martinez, Samantha Loutzenheiser, Simon W. Lam, Gary W. Procop, Sandra S. Richter, Elizabeth A. Neuner Tags: Original Research Article Source Type: research