Neuroendocrine Carcinoma of Gallbladder: A Step Beyond Palliative Therapy, Experience of 25 Cases

ConclusionsIn carefully selected patients of GB NECs, downsizing with NACT facilitates radical resection with negative margins.
Source: Journal of Gastrointestinal Cancer - Category: Cancer & Oncology Source Type: research

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Biomed Pharmacother. 2021 Aug 12;142:112025. doi: 10.1016/j.biopha.2021.112025. Online ahead of print.ABSTRACTCircular RNAs (circRNAs) have a closed loop structure which endows them high stability. These transcripts are made through back splicing instead of classical splicing and are abundant in the human transcriptome. Recent advances in the development and implementation of high-throughput sequencing methods in cooperation with novel bioinformatics tools have shown contribution of circRNAs in the developmental processes, physiological settings and pathoetiology of cancers. CircMTO1 is a circRNA which was firstly identifi...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Source Type: research
CONCLUSIONS: The present study shows the expression of molecular markers Her2 neu, p53, p16, survivin, COX-2, and EZH-2 in GBC. Now the time has come, and it is also the need of the day to establish early biomarkers of this highly lethal malignancy. It can be used in future for the detection of disease in the early phase and targeted therapy.PMID:34321957 | PMC:PMC8312376 | DOI:10.4103/jcar.JCar_4_21
Source: Journal of Carcinogenesis - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSIONS: Due to the non specific symptoms patients of GBC present at very advanced stages, high index of suspicion and health education seems to play an important role in early detection and improvement of survival.PMID:34321956 | PMC:PMC8312375 | DOI:10.4103/jcar.JCar_3_21
Source: Journal of Carcinogenesis - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSIONS: The present study shows the expression of molecular markers Her2 neu, p53, p16, survivin, COX-2, and EZH-2 in GBC. Now the time has come, and it is also the need of the day to establish early biomarkers of this highly lethal malignancy. It can be used in future for the detection of disease in the early phase and targeted therapy.PMID:34321957 | PMC:PMC8312376 | DOI:10.4103/jcar.JCar_4_21
Source: Journal of Carcinogenesis - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSIONS: Due to the non specific symptoms patients of GBC present at very advanced stages, high index of suspicion and health education seems to play an important role in early detection and improvement of survival.PMID:34321956 | PMC:PMC8312375 | DOI:10.4103/jcar.JCar_3_21
Source: Journal of Carcinogenesis - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSIONS: The present study shows the expression of molecular markers Her2 neu, p53, p16, survivin, COX-2, and EZH-2 in GBC. Now the time has come, and it is also the need of the day to establish early biomarkers of this highly lethal malignancy. It can be used in future for the detection of disease in the early phase and targeted therapy.PMID:34321957 | PMC:PMC8312376 | DOI:10.4103/jcar.JCar_4_21
Source: Journal of Carcinogenesis - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSIONS: Due to the non specific symptoms patients of GBC present at very advanced stages, high index of suspicion and health education seems to play an important role in early detection and improvement of survival.PMID:34321956 | PMC:PMC8312375 | DOI:10.4103/jcar.JCar_3_21
Source: Journal of Carcinogenesis - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSIONS: The present study shows the expression of molecular markers Her2 neu, p53, p16, survivin, COX-2, and EZH-2 in GBC. Now the time has come, and it is also the need of the day to establish early biomarkers of this highly lethal malignancy. It can be used in future for the detection of disease in the early phase and targeted therapy.PMID:34321957 | PMC:PMC8312376 | DOI:10.4103/jcar.JCar_4_21
Source: Journal of Carcinogenesis - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSIONS: Due to the non specific symptoms patients of GBC present at very advanced stages, high index of suspicion and health education seems to play an important role in early detection and improvement of survival.PMID:34321956 | PMC:PMC8312375 | DOI:10.4103/jcar.JCar_3_21
Source: Journal of Carcinogenesis - Category: Cancer & Oncology Authors: Source Type: research
CONCLUSIONS: The present study shows the expression of molecular markers Her2 neu, p53, p16, survivin, COX-2, and EZH-2 in GBC. Now the time has come, and it is also the need of the day to establish early biomarkers of this highly lethal malignancy. It can be used in future for the detection of disease in the early phase and targeted therapy.PMID:34321957 | PMC:PMC8312376 | DOI:10.4103/jcar.JCar_4_21
Source: Journal of Carcinogenesis - Category: Cancer & Oncology Authors: Source Type: research
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