Prevalence of health care–associated infections and antimicrobial resistance of the responsible pathogens in Ukraine: Results of a multicenter study (2014-2016)

ConclusionsHAIs and increasing antimicrobial resistance present a significant burden to the Ukraine hospital system. Infection control priorities in hospitals should include preventing surgical site infections, respiratory tract infections (which also include PNEU and LRTI), bloodstream infections, and urinary tract infections, as well preventing infections due to antimicrobial-resistant pathogens.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research

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Publication date: Available online 17 February 2020Source: Inorganica Chimica ActaAuthor(s): Priyaranjan Kumar, Ray J. Butcher, Ashis K. PatraAbstractHerein, we report physiochemical aspects, crystal structures, biological reactivity and interaction, DNA damage activity and preliminary antimicrobial properties of three metal complexes, [Co/Ni(dppz)2(sac)(H2O)]ClO4 [Co(II), 1; Ni(II), 2] and [Cu(dppz)2(sac)]ClO4 (3), where dppz is dipyrido[3,2-a:2′,3′-c]phenazine as potential photosensitizer and DNA intercalator and sac is artificial sweetener saccharin (o-sulfobenzimide). The solid-state structural analysis rev...
Source: Inorganica Chimica Acta - Category: Chemistry Source Type: research
Analyst, 2020, Accepted Manuscript DOI: 10.1039/D0AN00224K, PaperYanan Zhao, Dexin Zeng, Chao Yan, Wei Chen, Jianluan Ren, Yuan Jiang, Luyan Jiang, Feng Xue, Dejun Ji, Fang Tang, Mingqiang Zou, Jianjun Dai Escherichia coli O157:H7 is a severe foodborne pathogen that causes lots of life-threatening diseases. To search for a rapid, sensitive, portable and low-cost method detecting this pathogen, we developed a... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Analyst latest articles - Category: Chemistry Authors: Source Type: research
Condition:   Urinary Tract Infections Interventions:   Drug: Concentrated herbal extract granules TRA;   Drug: Placebo Sponsors:   Changhua Christian Hospital;   Ministry of Health and Welfare, Taiwan Completed
Source: - Category: Research Source Type: clinical trials
AbstractLung ultrasound (US) cannot be considered a new diagnostic imaging technique anymore, with some articles dating back 50  years. The question that hovers over it recently is why it is still not widely accepted, like chest radiography. So, have we wasted a lot of time without using lung US, or are we wasting our time using lung US? The main goals of this article are to underline all the advantages, potentials and reas ons to use lung US in everyday clinical practice, but also to address the main concerns linked to this imaging tool. From the standpoint of an experienced pediatric radiologist from a tertiary heal...
Source: Pediatric Radiology - Category: Radiology Source Type: research
Shine-Dalgarno (SD) motifs are thought to play an important role in translational initiation in bacteria. Paradoxically, ribosome profiling studies inE. coli show no correlation between the strength of an mRNA's SD motif and how efficiently it is translated. Performing profiling on ribosomes with altered anti-Shine-Dalgarno sequences, we reveal a genome-wide correlation between SD strength and ribosome occupancy that was previously masked by other contributing factors. Using the antibiotic retapamulin to trap initiation complexes at start codons, we find that the mutant ribosomes select start sites correctly, arguing that ...
Source: eLife - Category: Biomedical Science Tags: Chromosomes and Gene Expression Source Type: research
Source: Infection and Drug Resistance - Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research
ConclusionsInfection control priorities in hospitals should include prevention of surgical site infections, pneumonia, bloodstream infections and urinary tract infections. These results may help to delineate the requirements for infection prevention and control in acute care hospitals.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
Conclusion: Some Lactobacillus strains exhibit anti-CRE activity, which suggests potential applications for controlling or preventing CRE colonization or infection. Introduction Although Enterobacteriaceae are normal flora of the human intestinal system, they are also common pathogens causing human infections in the setting of both community-acquired and healthcare-associated infections (Hsueh et al., 2010; Toh et al., 2012; Lai et al., 2014; Jean et al., 2016). In this era of widespread antibiotic resistance, Enterobacteriaceae are no exception. Recently, the emergence of carbapenem-resistant Enterobacteriaceae (C...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusion This study revealed that Enterococcus species with biofilm potentials and extracellular virulence properties extensively occur in retail RTE shrimps. A significant number of isolated strains are resistant to antibiotics and harbor resistant and virulent genes, denoting a significant route of resistance and virulence dissemination to bacteria in humans. There is an inadequate understanding of the intricacies of antibiotic-resistant enterococci of food origin that belong to enterococci aside from E. faecium and E. faecalis. Findings from this study reveal detailed antibiotic resistance of E. durans, E. casselifla...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
In conclusion, we demonstrated that the selective boosting of lung innate immunity is a conceptually advantageous approach for improving the effectiveness of antibiotic treatment and fighting antibiotic-resistant bacteria. Introduction Pneumonia constitutes a major cause of death, morbidity and health resource use worldwide. The main causative agents identified in adult patients hospitalized for community-acquired pneumonia (CAP) are viruses (in 27–30% of cases, the most common being rhinovirus, influenza and coronavirus) and bacteria (14–23% of cases, with a marked predominance of Streptococcus pneumonia...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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