Management and Outcomes of Aortic Dissection in Pregnancy with Marfan syndrome: A Systematic Review.

CONCLUSIONS: Women with MFS are at high risk of aortic dissection during pregnancy and women with aortic root 41-45 mm should consider avoiding pregnancy. Guideline-specific management of aortic aneurysms in pregnancy will reduce the risk of dissection. Diagnosis and Management of MFS needs a multidisciplinary approach and team that should start working early in pregnancy. Further studies are needed to optimize medical and surgical approaches in addition to preconception counselling in high risk subjects. PMID: 30963974 [PubMed - as supplied by publisher]
Source: Current Vascular Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Curr Vasc Pharmacol Source Type: research

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Conclusions: The distribution of NICU beds between capital city and other cities of the State is adequate, considering Brazilian guidelines. However, there was a low adherence to the protocols for hypertensive and hemorrhagic emergencies, and a low coverage of humanization policies, pregnancy risk classification and ENC practices, especially breastfeeding in the first hour of life, and companion always during birth.RESUMO Objetivo: Descrever a estrutura e os processos de atendimento a gestante/rec ém-nascido, incluindo os componentes do Essential Newborn Care (ENC), das maternidades de Sergipe, Brasil. Método...
Source: Revista Paulista de Pediatria - Category: Pediatrics Source Type: research
Conclusion Labor induction was successful inmost patients. In the cases in which the final outcome was a cesarean section, the most strongly associated factors were: previous history of cesarean delivery, presence of fetuses with IUGR, and either excessively short or excessively long periods of induction.Resumo Objetivo Avaliar os resultados da indu ção de trabalho de parto e determinar os principais fatores associados à realização de cesarianas intraparto em pacientes do Hospital Universitário da Universidade Federal de Santa Catarina (HU-UFSC), Florianópolis, SC, Brasil. M...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
SUMMARY OBJECTIVE: To evaluate endocervical and vaginal environment changes in women using a levonorgestrel-releasing intrauterine system (LNG-IUS). METHODS: A quasi-experimental study included sixty women who had an LNG-IUS inserted in the Family Planning Clinic of UNICAMP between April and November of 2016. Women in reproductive age, non-pregnant, without the use of antibiotics and contraceptives seeking for LNG-IUS insertion were selected for this study. All women were evaluated with regard to vaginal and endocervical pH, vaginal and endocervical Gram-stained bacterioscopy, and Pap-smear before and two months after LNG-...
Source: Revista da Associacao Medica Brasileira - Category: General Medicine Source Type: research
Abstract OBJECTIVE: To investigate pregnancy outcomes, especially the risk of pregnancy-related aortic dissection (AD), in patients with Marfan syndrome (MFS) after prophylactic aortic root replacement (ARR). DESIGN: Retrospective case series study. SETTING: Tertiary perinatal care center at a university hospital. POPULATION: Pregnant women fulfilling the revised Ghent nosology (2010) criteria for MFS that were managed at our institute. METHODS: The pregnancy outcomes of all patients with MFS managed at our institute between 1982 and September 2016 were retrospectively reviewed based on medical...
Source: BJOG : An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Tags: BJOG Source Type: research
Abstract ObjectiveTo investigate pregnancy outcomes, especially the risk of pregnancy‚Äźrelated aortic dissection (AD), in patients with Marfan syndrome (MFS) after prophylactic aortic root replacement (ARR). DesignRetrospective case series study. SettingTertiary perinatal care center at a university hospital. PopulationPregnant women fulfilling the revised Ghent nosology (2010) criteria for MFS that were managed at our institute. MethodsThe pregnancy outcomes of all patients with MFS managed at our institute between 1982 and September 2016 were retrospectively reviewed based on medical records. Main Outcome MeasuresObstet...
Source: BJOG: An International Journal of Obstetrics and Gynaecology - Category: OBGYN Authors: Tags: Main Research Article Source Type: research
ConclusionTo the best of our knowledge, this is the first case of true abdominal aortic aneurysm repair and Caesarean section as a one-stage procedure.
Source: European Surgery - Category: Surgery Source Type: research
Background The risk of aortic complications associated with pregnancy in women with Marfan syndrome (MFS) is not fully understood. Methods and Results MFS women participating in the large National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) were evaluated. Among 184 women with MFS in whom pregnancy information was available, 94 (51%) had a total of 227 pregnancies. Among the women with pregnancies, 10 (10.6%) experienced a pregnancy-related aortic complication (4 type A and 3 type B dissections, 1 coronary artery dissection, and 2 with significant [≥3 mm] aort...
Source: JAHA:Journal of the American Heart Association - Category: Cardiology Authors: Tags: Pregnancy, Genetics, Aneurysm, Aortic Dissection Source Type: research
Abstract Half of acute aortic dissection in women under the age of 40 occurs during pregnancy or peripartum period. Marfan syndrome is the most common syndromic presentation of ascending aortic aneurysm, but other syndromes such as vascular Ehlers-Danlos syndrome, Loeys-Dietz syndrome and Turner syndrome also have ascending aortic aneurysms and the associated cardiovascular risk of aortic dissection and rupture. Management of aortic root aneurysm has been established in recent recommendations, even if levels of evidence are weak. Pregnancy and postpartum period should be followed very closely and determined to be ...
Source: Presse Medicale - Category: Journals (General) Authors: Tags: Presse Med Source Type: research
We present the case of a ruptured descending thoracic aortic aneurysm in a woman with Marfan syndrome who was 25 weeks pregnant. Emergent intervention was performed using an endovascular repair as a bridge to allow continuation of pregnancy, decreasing fetal morbidity, and allow subsequent later definitive open aortic repair. PMID: 26140774 [PubMed - in process]
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
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