Mitochondrial and satellite real time-PCR for detecting T. cruzi DTU II strain in blood and organs of experimentally infected mice presenting different levels of parasite load.

In conclusion, although kDNA qPCR achieved a better analytical sensitivity, sat-qPCR gave better specificity results. Nevertheless, further research is intended to test other T. cruzi DTUs and chagasic patients' samples before these cost-effective techniques are incorporated into diagnostic routines. PMID: 30904696 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30904696?dopt=Abstract

Source: Experimental Parasitology - March 19, 2019 Category: Parasitology Authors: Ferreira Filho JCR, Braz LMA, Andrino MLA, Yamamoto L, Kanunfre KA, Okay TS Tags: Exp Parasitol Source Type: research