Lyme neuroborreliosis in children: Report of nine cases and a review of the literature.

We report nine cases of pediatric neuroborreliosis collected by the National Observatory of Pediatric Bacterial Meningitis in France between 2001 and 2012. The nine children, aged 4-13 years, were identified in northern and eastern France and had the following clinical features: meningeal irritation alone or with facial palsy, or isolated facial palsy. All cases showed anti-Borrelia antibodies in cerebrospinal fluid or serum, or with a positive Borrelia PCR in the CSF. The outcome was favorable in all cases after a 2- to 3-week course of third-generation cephalosporin. On the basis of these nine pediatric cases, this study provides an update on the epidemiology, pathophysiology, diagnostic strategy, and treatment of neuroborreliosis, with insight into the specific features of pediatric neuroborreliosis and the difficulties encountered in the diagnosis of this infection.
PMID: 30885602 [PubMed - as supplied by publisher]

Source: Archives de Pediatrie - March 14, 2019 Category: Pediatrics Authors: Guet-Revillet H, Levy C, Vallet C, Maghraoui-Slim V, Dommergues MA, Hentgen V, Paget C, Laugel V, Cohen R, Ferroni A Tags: Arch Pediatr Source Type: research