Lyme neuroborreliosis in children: Report of nine cases and a review of the literature.
We report nine cases of pediatric neuroborreliosis collected by the National Observatory of Pediatric Bacterial Meningitis in France between 2001 and 2012. The nine children, aged 4-13 years, were identified in northern and eastern France and had the following clinical features: meningeal irritation alone or with facial palsy, or isolated facial palsy. All cases showed anti-Borrelia antibodies in cerebrospinal fluid or serum, or with a positive Borrelia PCR in the CSF. The outcome was favorable in all cases after a 2- to 3-week course of third-generation cephalosporin. On the basis of these nine pediatric cases, this study provides an update on the epidemiology, pathophysiology, diagnostic strategy, and treatment of neuroborreliosis, with insight into the specific features of pediatric neuroborreliosis and the difficulties encountered in the diagnosis of this infection. PMID: 30885602 [PubMed - as supplied by publisher]
Publication date: Available online 19 February 2020Source: International Journal of Gastronomy and Food ScienceAuthor(s): Máirtín Mac Con Iomaire
This study compares the development of prosodic processing in French- and German-learning infants. The emergence of language-specific perception of phrase boundaries was directly tested using the same stimuli across these two languages. French-learning (Experiment 1, 2) and German-learning 6- and 8-month-olds (Experiment 3) listened to the same French noun sequences with or without major prosodic boundaries ([Loulou et Manou][et Nina]; [Loulou et Manou et Nina], respectively). The boundaries were either naturally cued (Experiment 1), or cued exclusively by pitch and duration (Experiment 2, 3). French-learning 6- and 8-mont...
France hosts approximately 368,000 'persons of concern' (e.g. refugees, stateless, people in refugee-like situations, asylum-seekers). Northern France has become a focal area, due to its proximity to the Dover entry-point to the UK and larger numbers of mi...
Condition: Hyperoxia Intervention: Sponsor: University Hospital, Strasbourg, France Recruiting
To ascertain the safety and mid-term outcomes of RotarexS rotational atherectomy plus thrombectomy device (Straub Medical AG, Wangs, Switzerland) with or without adjunctive treatment (e.g., percutaneous transluminal angioplasty, PTA/Drug-coated balloon, DCB/stenting) in patients with in-stent restenosis (ISR) or occlusion in the iliac and/or infrainguinal arteries.
Venous thrombosis in a pediatric population can be multifactorial such as secondary to extrinsic compression syndromes: Paget-Schroetter syndrome, May-Thurner syndrome (iliac vein thrombosis), hypercoagulable state, PICC or other central venous catheters and can also occur in patients with arteriovenous fistulae or grafts in patients requiring long-term hemodialysis. DVT affects 0.07-0.14 in 10,000 children annually;58 per 10,000 in hospitalized children. Catheter-directed thrombolysis (CDT), venous angioplasty, stent placement, and mechanical thrombectomy are used to treat both acute and chronic venous thrombosis.
Liver fibrosis is a progressive disease of varying etiologies affecting millions worldwide. Several noninvasive tests have been developed to monitor liver fibrosis (using the METAVIR scale F0 [normal] to F4 [cirrhosis]) to address the need for repeated liver biopsies. FibroTest (FT; BioPredictive, France), a panel of 6 laboratory tests, and Shear Wave Elastography (SWE; GE, USA), an ultrasound evaluation of tissue stiffness via shear force measurements, are utilized in our health system to diagnose and monitor liver fibrosis.
ConclusionThis expert-based consensus conference provides recommendations to standardise the imaging protocol for computed tomography urography.Key Points•To improve excretory phase imaging, an intravenous injection of furosemide should be performed before the injection of iodinated contrast medium.•Systematic oral or intravenous hydration is not necessary to improve excretory phase imaging.•The choice between single-bolus and split-bolus protocols depends on the context, but split-bolus protocols should be favoured whenever possible to decrease patient irradiation.
In conclusion, these findings disclosePFN1 haploinsufficiency as the pathological mechanism in OS/PDB. © 2020 American Society for Bone and Mineral Research.
LYME disease is a bacterial infection which could lead to severe physical and mental problems if not diagnosed at an early stage. Spotting the early warning signs will ensure prompt treatment and noticing this peculiar feeling in the head could mean you're at risk.