Gene Expression in Ex Vivo Perfused Porcine Hearts: Identification of a Molecular Injury-Repair Response

Cardiac transplantation is a life-saving intervention for advanced heart failure but it is limited by a shortage of suitable donor organs. Ex vivo heart perfusion (EVHP) represents a promising alternative for organ preservation and repair. We aimed to assess the utility of gene expression for better understanding and monitoring cardiac injury and repair during EVHP.

Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: S. Rotich, N. Herbers, S. Hatami, M. Mengel, J. Nagendran, D.H. Freed, B. Adam Tags: 433 Source Type: research