Single-center study of Lynch syndrome screening in colorectal polyps

ConclusionImmunohistochemical detection of colorectal polyp mismatch repair protein as Lynch syndrome screening efficiency is low. Effective screening strategies may be improved by optimizing patient/polyp selection, such as focusing on young adenoma patients with a family history of cancer, or patients who present with high-risk features (large size, villous, high-grade dysplasia and malignant components).
Source: Hereditary Cancer in Clinical Practice - Category: Cancer & Oncology Source Type: research