Implications of Oxalate as a Novel Risk Factor for Chronic Kidney Disease

One in 7 Americans (approximately 30 million individuals) has chronic kidney disease (CKD). Beyond heightened risk of end-stage renal disease, these individuals are at high risk of cardiovascular disease, frailty, cognitive impairment, and premature death. Chronic kidney disease is widely recognized as a major public health concern in both the United States and worldwide. Diabetes is the most common cause of CKD, and most epidemiology texts list hypertension as the second most common cause. However, some experts believe that hypertension may in fact be the consequence rather than the cause of this large fraction of CKD, and in the absence of biopsy data in most patients, the actual cause remains unclear. Identifying novel risk factors for the development and progression of CKD is important, particularly if such factors are common in the population and modifiable.
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research

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Source: Intensive Care Medicine - Category: Intensive Care Source Type: research
Hyperuricemia and gout have been linked to chronic kidney disease (CKD). Whether the increased risk of CKD in gout is due to shared risk factors such as hypertension, diabetes or heart disease, or due to gout its...
Source: BMC Nephrology - Category: Urology & Nephrology Authors: Tags: Research article Source Type: research
Abstract Lower extremity peripheral artery disease (PAD) affects 12% to 20% of Americans 60 years and older. The most significant risk factors for PAD are hyperlipidemia, hypertension, diabetes mellitus, chronic kidney disease, and smoking; the presence of three or more factors confers a 10-fold increase in PAD risk. Intermittent claudication is the hallmark of atherosclerotic lower extremity PAD, but only about 10% of patients with PAD experience intermittent claudication. A variety of leg symptoms that differ from classic claudication affects 50% of patients, and 40% have no leg symptoms at all. Current guidelin...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
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Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
Listen: Mayo Clinic Radio 3/9/19 March is National Kidney Month -- an awareness effort to encourage people who are at risk of chronic kidney disease, often due to diabetes or high blood pressure, to get screened.?On the Mayo Clinic Radio podcast, Dr. Ladan Zand, a Mayo Clinic nephrologist, discusses?chronic kidney disease and?offers tips to keep [...]
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news
Abstract OBJECTIVE: To analyze risk factors, temporality, and outcomes for women readmitted postpartum for a hypertensive indication who did not have a hypertensive diagnosis during their delivery hospitalization. METHODS: The Healthcare Cost and Utilization Project's Nationwide Readmissions Database for 2010-2014 was used to evaluate risk for postpartum readmission for preeclampsia and hypertension within 60 days of discharge from a delivery hospitalization among women without these diagnoses during delivery in this cohort study. Obstetric, medical, demographic, and hospital factors associated with postpartu...
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
CONCLUSION: - In long-term-treated HIV-infected patients with frequent comorbid conditions, oxidative stress could be contributing to diabetes and LDL-related and atherogenic dyslipidaemias independently of inflammation. PMID: 30862472 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - Category: Endocrinology Authors: Tags: Diabetes Metab Source Type: research
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Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
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Source: European Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Eur J Pharmacol Source Type: research
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