Using histones as bait: How do cells decide how to repair their DNA?

(Helmholtz Zentrum M ü nchen - German Research Center for Environmental Health) When DNA in the cell nucleus gets damaged, our cells can resort to a variety of repair mechanisms. A recent study published in 'Nature Cell Biology', to which scientists from Helmholtz Zentrum M ü nchen made major contributions, elucidates the molecular basis by which a cell makes the choice between these repair mechanisms. The trick the scientists used: they developed a molecular bait to literally fish out the relevant proteins from the cell nucleus.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news