Glucose-6-phosphatase Expression –Mediated [ 18 F]FDG Efflux in Murine Inflammation and Cancer Models

ConclusionsThere was no difference in the pattern of [18F]FDG accumulation with time in MDA-MB-231 tumors and inflammatory lesions. We found that [18F]FDG efflux accelerated in activated macrophages reflecting increased G6Pase expression after activation and lower expression of HK II protein than that in MDA-MB-231 cancer cells.

http://link.springer.com/10.1007/s11307-019-01316-7

Source: Molecular Imaging and Biology - February 4, 2019 Category: Molecular Biology Source Type: research