Surface evaluation of titanium oxynitride coatings used for developing layered cardiovascular stents

Publication date: June 2019Source: Materials Science and Engineering: C, Volume 99Author(s): Nataliia Beshchasna, Au Yeung Kwan Ho, Muhammad Saqib, Honorata Kraśkiewicz, Łukasz Wasyluk, Oleg Kuzmin, Oana Cristina Duta, Denisa Ficai, Roxana Doina Trusca, Anton Ficai, Vladimir F. Pichugin, Jörg Opitz, Ecaterina AndronescuAbstractStents are important medical devices used to increase the quality and life expectancy of patients with heart diseases and stroke, leading causes of death, worldwide. In order to minimize the risk of restenosis, different coating on bare metal stents (BMS) such as polymer coatings; titanium dioxide, titanium nitride or titanium oxynitride coatings; carbon coatings and others are used. The aim of this work was to develop novel stents coated with titanium oxynitride (TiOxNy) with optimal chemical, mechanical and biological properties having possibly good coverage rate of inner and outer stent surfaces. The improvement should be achieved by optimization and development of a magnetron sputtering deposition technology. The goal of the study is understanding of the existing potential for improvement of the deposition technology and the coating quality itself. For this study, different O2/N2 ratios, meaning 1/2, 1/5 and 1/10 (the ratios of reagent gasses are given for the values of mass flows into the chamber) has been selected. Stability in simulated body fluids, surface morphology and protein adsorption as well as preliminary cytotoxic behaviour of the sam...
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research