Unedited microneurosurgery of a mixed germ cell tumor of the pineal region.

Conclusion: This unedited video offers all detailed aspects that a neurosurgeon as the senior author JH considers essential when performing an efficient and safe surgery for a mixed germ cell tumor. Videolink: http://surgicalneurologyint.com/videogallery/pineal-tumor-5. PMID: 30687573 [PubMed]
Source: Surgical Neurology International - Category: Neurosurgery Tags: Surg Neurol Int Source Type: research

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Publication date: Available online 20 November 2019Source: Urology Case ReportsAuthor(s): Eric M. Chevli, Tyler J. Maiers, David J. Abramowitz, Shervin Badkhshan, John J. BodkinAbstract:Situs inversus totalis (SIT) is a rare condition with left-right mirror imaging of both abdominal and thoracic organs. While this configuration is rarely of medical importance, an understanding of this unique anatomy is essential in the setting of surgical intervention. Here we review a case of renal cell carcinoma (RCC) in the setting of SIT. The patient underwent a hand-assisted laparoscopic radical nephrectomy. Pathology revealed pT3aNxM...
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
OBJECTIVES: The suicide crisis is a relatively short-lived psychiatric emergency, with transient symptoms that ebb and flow around the suicide attempt.Understanding the dynamic processes of symptoms before and after suicide attempt may aid future preventio...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news
Conclusions: Buparlisib was well tolerated, however efficacy was limited despite selection of PI3K pathway aberrations. Future studies may provide insight into buparlisib efficacy by refining the molecular selection of different tumor types. PMID: 31741715 [PubMed]
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
ConclusionsOur study showed that machine learning-based multiparametric MR imaging radiomics could accurately distinguish aggressive from non-aggressive PTC preoperatively. This approach may be helpful for informing treatment strategies and prognosis of patients with aggressive PTC.
Source: European Journal of Radiology - Category: Radiology Source Type: research
We report a unique case of breast GCT-ST coincident with ductal carcinoma in situ (DCIS), diagnosed with histological, immunohistochemical, and H3F3A (Histone H3.3) mutation analyses. A 59-year-old woman preoperatively diagnosed with DCIS underwent total mastectomy for a cystic mass. Histology revealed a tumor composed of mononuclear cells interspersed with numerous osteoclast-like giant cells, resembling giant cell tumor of bone (GCT-B), with apocrine DCIS in proximity to the tumor. The mononuclear and giant cells were immunoreactive for CD68 and negative for cytokeratins. Granulomatous diseases, carcinomas with giant cel...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
Conclusions: IENFD measurement in postmortem skin is feasible and may be used to study the epidemiology of SFN.
Source: Journal of Clinical Neuromuscular Disease - Category: Neurology Tags: Original Article Source Type: research
Condition:   Carcinoma, Non-Small-Cell Lung Interventions:   Drug: Metformin;   Other: No metformin Sponsors:   Ethisch Comité, UZA;   Stand Up To Cancer Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Hepatocellular Carcinoma Interventions:   Drug: Regorafenib;   Drug: Nivolumab Sponsors:   Fundacion Clinic per a la Recerca Biomédica;   Apices Soluciones S.L. Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Mild Dysplasia of Esophagus;   Moderate Dysplasia of Esophagus;   Severe Dysplasia of Esophagus;   Carcinoma in Situ of Esophagus;   Esophageal Squamous Cell Carcinoma Intervention:   Diagnostic Test: Endoscopic examination using white light, NBI and iodine staining Sponsor:   Beijing Cancer Hospital Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Hepatocellular Carcinoma Interventions:   Procedure: Systemic chemotherapy;   Drug: Lenvatinib;   Drug: Toripalimab Sponsor:   Sun Yat-sen University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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