Renal Medullary Carcinoma: a Report of the Current Literature

We present an updated report of renal medullary carcinoma (RMC), a rare and aggressive condition.Recent FindingsThere is a majority of male patients, of African descent, in the second or third decade of life. In differential diagnosis, other tumors, such as malignant rhabdoid tumor (MRT), vinculin-anaplastic lymphoma kinase (VCL-ALK) translocation renal cell carcinoma, and collecting duct carcinoma, may present difficulties. Abnormalities of tumor suppressor gene SMARCB1 have been found in RMC. Reported symptoms were hematuria, pain, weight loss, respiratory distress, palpable mass, cough, and fever. Most patients present with metastases at diagnosis. There is no definite recommended treatment, and protocols are extrapolated from other malignancies, with nephrectomy and systemic therapies being most frequently used. Response to treatment and prognosis remain very poor.SummaryRMC is a rare and aggressive tumor. Definitive diagnosis requires histological assessment and the presence of sickle-cell hemoglobinopathies.
Source: Current Urology Reports - Category: Urology & Nephrology Source Type: research

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Conclusions: Our findings provide new evidence on patterns of behavioral modification in a population-based sample of Latinos diagnosed with chronic health conditions. Findings suggest the need to promote language and culturally relevant initiatives to increase the adoption of health-enhancing behaviors and improve chronic disease management among Spanish-speaking Latinos.
Source: Medical Care - Category: Health Management Tags: Original Articles Source Type: research
Targeted muscle reinnervation (TMR), originally developed as an experimental technique for prosthetic control, has been shown to be safe and effective for the treatment and prevention of postamputation pain. Targeted muscle reinnervation involves coaptatio...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
I’ve been doing RFAs in private practice for 5 years, never any complications. Today, I slipped off the left L4 pedicle a few times, it was challenging. Adjusted the fluoro and was satisfied. No motor, lateral image did not indicate foraminal encroachment. Injected lidocaine prior to ablation. I was firmly in os and I held the probe the entire 2:30. In PACU patient complained of weakness and numbness in the L4 dermatome (FML). I was hoping it could be chalked up to the lidocaine... RFA complication
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
Hi folks, Does anyone have good recommendations for favorite electives during fellowship? My program has slots for three 2-week rotations -- it is a large tertiary center with a lot of services (i.e. plenty of options). I imagine there are pearls and valuable skills to take away from nearly all available rotations. In your experience, any particularly high-yield to the practice of HPM? I'm thinking addictions, pain, .... spiritual? psych?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Hospice and Palliative Medicine Source Type: forums
Abstract BACKGROUND AND OBJECTIVES: Citrus fruit are suggested to be associated with reduced risk of nasopharyngeal carcinoma (NPC), but findings from epidemiologic studies have been inconsistent. We aimed to synthesize the association by conducting a meta-analysis of existing evidence. METHODS AND STUDY DESIGN: Databases including Medline, EMBASE, Web of science, and the Cochrane Library were searched for eligible studies up to March 2019 using a series comprehensive searching terms. The adjusted odds ratios (ORs) of citrus fruit intake with NPC risk from each study were extracted to calculate a pooled assoc...
Source: Asia Pacific Journal of Clinical Nutrition - Category: Nutrition Authors: Tags: Asia Pac J Clin Nutr Source Type: research
Publication date: December 2019Source: British Journal of Oral and Maxillofacial Surgery, Volume 57, Issue 10Author(s): Carrie Newlands, Jason Thompson, Charlotte Proby, Sian Lax Williams, Catherine Harwood, Kate Fife, Jeremy Marsden, Agata Rembliak
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
Publication date: December 2019Source: British Journal of Oral and Maxillofacial Surgery, Volume 57, Issue 10Author(s): David McGoldrick, Alica Torres-Rendon, Raj Sandhu, Gary Walton
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
Publication date: December 2019Source: British Journal of Oral and Maxillofacial Surgery, Volume 57, Issue 10Author(s): Ahmed Abdelrahman, Nikola dimitrovpetrov, Daya Gahir
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
Publication date: December 2019Source: British Journal of Oral and Maxillofacial Surgery, Volume 57, Issue 10Author(s): Leh Chuan Lim, Pavan Padaki, Shakeel Akhtar
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
Publication date: December 2019Source: British Journal of Oral and Maxillofacial Surgery, Volume 57, Issue 10Author(s): James Webster, Alice Cameron, Serryth Colbert
Source: British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Source Type: research
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