Trends of elevated parathormone serum titers in hemodialysis patients on intensive therapy for bone disease: A multicenter study.

Trends of elevated parathormone serum titers in hemodialysis patients on intensive therapy for bone disease: A multicenter study. Saudi J Kidney Dis Transpl. 2014 Nov-Dec;25(6):1166-77 Authors: Karkar A, Sinha AK, Abdelrahman M, Mushtaque F, Awn NM, Qadi Y, Nassar M, Algareeb A, Taha MI, Abdulkader M, Sabry A, Souqiyyeh MZ, Shaheen FA Abstract To determine the prevalence of controlled parathyroid hormone (PTH) serum levels with intensified therapy for chronic kidney disease mineral and bone disorder (CKD-MBD) in the dialysis population, we studied 563 chronic hemodialysis patients recruited from three different dialysis centers from three different major cities in the Kingdom of Saudi Arabia. The trend of the routine monthly chemistries related to CKD-MBD was evaluated besides the whole-molecule PTH serum levels over 28 months (January 2011 to April 2013). The cost ratios of the medications to the estimated dialysis total cost were calculated. There were 323 (57.4%) males in the study, and the mean age of the patients was 50.2 ± 15.2 years; 371 (65.9%) patients were initiated on dialysis before 2011. The causes of the original kidney disease included diabetes mellitus in 163 (29%) patients. Parathyroidectomy was performed in 23 (4.1%) patients and only six (23%) patients underwent the operation during the study period; most of the parathyroidectomies (69%) were performed before 2011. The trend of the medians of monthly serum levels ...
Source: Saudi Journal of Kidney Diseases and Transplantation - Category: Urology & Nephrology Authors: Tags: Saudi J Kidney Dis Transpl Source Type: research