Angiotensinogen and Megalin Interactions Contribute to Atherosclerosis.

Conclusions- These results reveal a regulatory role of megalin in the intrarenal renin-angiotensin homeostasis and atherogenesis, positing renal Ang II to be an important contributor to atherosclerosis that is mediated through AGT and megalin interactions. PMID: 30567480 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30567480?dopt=Abstract

Source: Arteriosclerosis, Thrombosis and Vascular Biology - December 20, 2018 Category: Cardiology Authors: Ye F, Wang Y, Wu C, Howatt DA, Wu CH, Balakrishnan A, Mullick AE, Graham MJ, Danser AHJ, Wang J, Daugherty A, Lu HS Tags: Arterioscler Thromb Vasc Biol Source Type: research