Dilated Cardiomyopathy in 151 Irish Wolfhounds: Characteristic Clinical Findings, Life Expectancy and Causes of Death

The objective of this study was to investigate survival and causes of death in IW with DCM and to characterize the clinical findings of DCM over time. Data from cardiovascular examinations performed in 1591 IW, including echocardiography and electrocardiography, were retrospectively evaluated. IW with DCM on medical therapy with long term longitudinal follow-up were included in this study (n = 151; 95 males, 56 females). Based on their clinical status at initial diagnosis, IW were classified into one of three groups: preclinical DCM with sinus rhythm (PC-DCM-SR, n = 35), preclinical DCM with atrial fibrillation (PC-DCM-AF, n = 87), and congestive heart failure with DCM and AF (CHF-DCM-AF, n = 29). Survival data were analyzed using cumulative incidence functions, Kaplan-Meier and Cox regression.CHF was predominantly characterized by chylous pleural and mild pericardial effusions. Causes of death were cardiac (CD) in 73/151 and non-cardiac (non-CD) in 62/151; 16 dogs remained alive at study end. The majority of deaths in both preclinical DCM groups were non-CD (PC-DCM-AF = 51.9% non-CD, 48.1% CD; PC-DCM-SR, 65.5% non-CD, 34.5% CD). In the CHF-DCM-AF group most dogs (89.6%) experienced a CD. Median survival of the CHF-DCM-AF group (7.3 months) was significantly shorter than in the PC-DCM-AF group (21.9 months) or PC-DCM-SR group (29.1 months, P = 0.001).CHF-DCM-AF in IW was associated with reduced life expectancy and CD...
Source: The Veterinary Journal - Category: Veterinary Research Source Type: research

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Source: Journal of Veterinary Cardiology - Category: Veterinary Research Source Type: research
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Please wait while the activity loads. If this activity does not load, try refreshing your browser. Also, this page requires javascript. Please visit using a browser with javascript enabled. If loading fails, click here to try again Click on the 'Start' button to begin the mock test. After answering all questions, click on the 'Get Results' button to display your score and the explanations. There is no time limit for this mock test. Start Congratulations - you have completed DM / DNB Cardiology Entrance Mock Test 7. You scored %%SCORE%% out of %%TOTAL%%. Your performance has been rate...
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