Mandibular osteonecrosis/osteomylitis in a patient with crohn disease

DiscussionPrednisone and adalimumab are often used in the treatment of CD, resulting in a low incidence of osteonecrosis. Infection resulting from immunosuppression is one of the side effects of adalimumab. The relationship between corticosteroid use and osteonecrosis still needs investigation. Patients with CD and a history of steroid or immunosuppressive drug use should to be observed for osteonecrotic lesions of the jaw, mainly after dental procedures.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research