EZH2 Expression is increased in BAP1-mutant renal clear cell carcinoma and is related to poor prognosis

Conclusion: CcRCC with decreased BAP1 level has poor prognosis and is associated with higher EZH2 expression. Inhibition of EZH2 in BAP1-mutated entity holds promise for further investigation.

Source: Journal of Cancer - December 14, 2018 Category: Cancer & Oncology Authors: Chenmin Sun, Chunchun Zhao, Shugen Li, Jianqing Wang, Qidong Zhou, Jianliang Sun, Qiang Ding, Min Liu, Guanxiong Ding Tags: Research Paper Source Type: research