The effect of chronic kidney disease on lipid metabolism

AbstractThe major cause of death among chronic kidney disease patients is cardiovascular diseases. Cardiovascular and kidney disease are interrelated and increase the severity of each other. Dyslipidemia is one the major causes of cardiovascular disease among chronic kidney disease patients along with diabetes and hypertension. The relationship between dyslipidemia and chronic kidney disease is reciprocal. Dyslipidemia is known to be a risk factor for chronic kidney disease and chronic kidney disease causes major alterations on lipoprotein profile, defined as the “dyslipidemic profile” of chronic kidney disease patients. Increased triglyceride, very low density lipoprotein and oxidized low density lipoprotein as well as decreased high density lipoprotein and changes in the composition of lipoproteins contribute to the “dyslipidemic profile.” Treatmen t strategies targeting the “dyslipidemic profile” of chronic kidney disease could contribute to prevent cardiovascular diseases. Current therapy is based on the patient kidney function and consist mainly of statins. This review focuses on the effects of chronic kidney disease on the lipoprotein profile and how this may impact novel therapeutic approaches to cardiovascular risk.
Source: International Urology and Nephrology - Category: Urology & Nephrology Source Type: research

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Source: Presse Medicale - Category: General Medicine Authors: Tags: Presse Med Source Type: research
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Source: Medical Journal of Australia - Category: General Medicine Tags: Med J Aust Source Type: research
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Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
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Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research
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Source: Health Affairs Blog - Category: Health Management Authors: Tags: Drugs and Medical Innovation chronic disease comparative effectiveness research efficacy-effectiveness gap health care innovation measuring care value randomized controlled trials real-world evidence Source Type: blogs
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Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
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Source: Hypertension - Category: Cardiology Authors: Tags: Poster Abstract Presentations Source Type: research
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Source: Current Opinion in Nephrology and Hypertension - Category: Urology & Nephrology Tags: MOLECULAR CELL BIOLOGY AND PHYSIOLOGY OF SOLUTE TRANSPORT: Edited by Alan S.L. Yu Source Type: research
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Source: Clinical and Experimental Hypertension - Category: Cardiology Authors: Tags: Clin Exp Hypertens Source Type: research
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Source: Indian Journal of Nephrology - Category: Urology & Nephrology Authors: Source Type: research
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