Management of Diffuse Large B Cell Lymphoma in the Oldest Old--Insight into the Management Decision Process: A Canadian Perspective

Conclusion: Very elderly DLBCL patients, despite their advanced age, still have a significant survival benefit when treated with systemic chemotherapy. In our study, main factors contributing to overall survival were ECOG status and aaIPI as they are known to be important considerations in the management decision process. Interestingly, comorbidities, as measured by the Charlson score, do not seem as important in the management decision process. Instead, geriatric syndromes, some of them potentially reversible, appear to play an important role.DisclosuresPavic: Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; BMS: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Novartis: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; AstraZeneca: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Roche: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Research Funding.

Source: Blood - November 21, 2018 Category: Hematology Authors: Lacerte, A., Bleau, M.-P., Castilloux, J.-F., De-angelis, F., Desjardins, P., Pavic, M., Fulop, T. Tags: 627. Aggressive Lymphoma (Diffuse Large B-Cell and Other Aggressive B-Cell Non-Hodgkin Lymphomas)-Results from Retrospective/Observational Studies: Poster III Source Type: research