Population pharmacokinetics of FOLFIRINOX: a review of studies and parameters

ConclusionsThe current review allows for a global understanding of FOLFIRINOX pharmacokinetics, and will provide a basis for further development of pharmacokinetics –pharmacodynamics–toxicity models for model-driven FOLFIRINOX protocol optimization to reach the best benefit-to-risk ratio.
Source: Cancer Chemotherapy and Pharmacology - Category: Cancer & Oncology Source Type: research