Genetic polymorphism of glial cell derived neurotrophic factor (GDNF) in male infertility.

Genetic polymorphism of glial cell derived neurotrophic factor (GDNF) in male infertility. Br J Biomed Sci. 2018 Nov 08; Authors: Shabani S, Mashayekhi F, Shahangian SS, Salehi Z PMID: 30406716 [PubMed - as supplied by publisher]
Source: British Journal of Biomedical Science - Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research

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This study aimed to investigate the clinical factors affecting pregnancy rates following the surgical removal of intrauterine adhesions (IUAs) and subsequent in vitro fertilization and embryo transfer (IVF-ET). We retrospectively evaluated case data from patients who had undergone hysteroscopic surgery to remove varying degrees of IUAs and who had subsequently received assisted reproductive treatments with IVF-ET (in all 140 cycles) at our hospital between January, 2011 and January, 2015. The patient data were divided into either the pregnancy or non-pregnancy groups based on the pregnancy outcomes, and a number of clinico...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
ConclusionThese results suggest that MHT ameliorates the symptoms of PCOS by improving the dysregulation of ovarian steroids and steroidogenic enzymes in PCOS rats.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
ilde;o MEOD Abstract Sperm DNA fragmentation is referred to as one of the main causes of male infertility. Failures in the protamination process, apoptosis and action of reactive oxygen species (ROS) are considered the most important causes of DNA fragmentation. Action of ROS or changes in sperm protamination would increase the susceptibility of sperm DNA to fragmentation. Routine semen analysis is unable to estimate sperm chromatin damage. Sperm DNA integrity influences sperm functional capability, therefore tests that measure sperm DNA fragmentation are important to assess fertility disorders. Actually, there is...
Source: Zygote - Category: Reproduction Medicine Authors: Tags: Zygote Source Type: research
In conclusion, our study showed that the frequency of Y chromosome microdeletion in male patients in Japan was similar to that reported in patients from other countries, and SRR was higher in patients with AZFc deletion. PMID: 31603142 [PubMed - as supplied by publisher]
Source: Asian Journal of Andrology - Category: Urology & Nephrology Authors: Tags: Asian J Androl Source Type: research
Publication date: October 2019Source: European Urology Supplements, Volume 18, Issue 9Author(s): L. Boeri, P. Capogrosso, E. Ventimiglia, W. Cazzaniga, E. Pozzi, N. Schifano, F. Chierigo, C. Abbate, F. Gaboardi, E. Montanari, F. Montorsi, A. Salonia
Source: European Urology Supplements - Category: Urology & Nephrology Source Type: research
Publication date: October 2019Source: European Urology Supplements, Volume 18, Issue 9Author(s): E. Ventimiglia, P. Capogrosso, L. Boeri, W. Cazzaniga, M. Alfano, F. Chierigo, E. Pozzi, R. Matloob, C. Abbate, P. Viganò, F. Gaboardi, F. Montorsi, A. Salonia
Source: European Urology Supplements - Category: Urology & Nephrology Source Type: research
Publication date: October 2019Source: European Urology Supplements, Volume 18, Issue 9Author(s): W. Cazzaniga, P. Capogrosso, E. Ventimiglia, L. Boeri, E. Pozzi, F. Chierigo, N. Schifano, F. Belladelli, R. Zuabi, C. Abbate, F. Gaboardi, F. Montorsi, A. Salonia
Source: European Urology Supplements - Category: Urology & Nephrology Source Type: research
Authors: Homma T, Takeda Y, Sakahara S, Ishii N, Kobayashi S, Abe H, Asao H, Fujii J Abstract New Zealand white (NZW) mouse is a mutant strain that has a larval defect in the immune system, and an F1 hybrid between NZW and New Zealand Black mouse spontaneously develops systemic lupus erythematosus (SLE). In meantime the ablation of superoxide dismutase 1 (Sod1) causes autoimmune hemolytic anemia, a clinical condition of SLE, in mice with a C57BL/6 background. Based on our previous studies, we hypothesized that oxidative stress may trigger this aberrant autoimmunity in NZW mice without crossing with another strain. ...
Source: Free Radical Research - Category: Research Tags: Free Radic Res Source Type: research
This is a very common misconception.Part of the reason is that twins are far more memorable than singletons. This is specially true if the birth of the twins has happened after many years of infertility , because of IVF.On the other hand, singleton IVF pregnancies are not very memorable - and infertile couples will often not even share the information that they did IVF to get pregnant.Also, multiple pregnancies after IVF used to be much commoner in the past , because many IVF clinics would transfer multiple embryos at one time. They didn't have very good success rates, and in order to increase the chances of succ...
Source: Dr.Malpani's Blog - Category: Reproduction Medicine Source Type: blogs
Publication date: Available online 13 August 2019Source: Reproductive BioMedicine OnlineAuthor(s): J Bellver, E Bosch, J.J Espinós, F Fabregues, J Fontes, J García-Velasco, J Llácer, A Requena, M.A Checa, Spanish Infertility SWOT Group (SISG)AbstractSecond-generation preimplantation genetic testing for aneuploidy (PGT-A 2.0) in patients with an unfavourable reproductive and IVF prognosis is becoming common practice, with the aim of improving reproductive outcomes. However, there is still no clear evidence on the possible advantages and drawbacks with regard to this procedure. In this discussion paper, ...
Source: Reproductive BioMedicine Online - Category: Reproduction Medicine Source Type: research
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