A systematic review of single-dose aminoglycoside therapy for urinary tract infection: Is it time to resurrect an old strategy?

Conclusions: Single-dose aminoglycoside therapy appears to be an effective treatment option for lower UTI in non-septic patients, with minimal toxicity. Additional studies would be beneficial to confirm efficacy for pyelonephritis. When resistance to first-line UTI agents is endemic, aminoglycosides may serve as β-lactam and fluoroquinolone-sparing options. PMID: 30397061 [PubMed - as supplied by publisher]
Source: Antimicrobial Agents and Chemotherapy - Category: Microbiology Authors: Tags: Antimicrob Agents Chemother Source Type: research