Imaging cardiac innervation in hereditary transthyretin (ATTRm) amyloidosis: A marker for neuropathy or cardiomyopathy in case of heart failure?

ConclusionIn case of heart failure,123I-MIBG scintigraphy reflects cardiomyopathy rather than cardiac autonomic neuropathy in ATTRm patients and TTR mutation carriers.123I-MIBG scintigraphy may already be abnormal before any cardiac bone tracer uptake is visible.
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research