Glympse Bio raises $22M for disease-detecting sensors

Sensor-driven disease detection company Glympse Bio has raised $22 million in a Series A round to fund clinical trials for its technology. The Cambridge, Mass.-based company uses bioengineered activity sensors transported to the site of disease in patients to investigate biological targets such as proteases – a class of enzymes that drive critical disease pathways. Once a disease is located, the sensor emits a signal that can be detected noninvasively from the recipient’s urine, according to the company. A spinout from Massachusetts Institute of Technology, Glympse Bio is applying machine learning algorithms to develop a proprietary, whole-genome database of enzymes and sensors capable of targeting all clinically-relevant proteases. Its technology platform can be extended to multifunctional enzymes including kinases, glycases, and lipases that may indicate the presence of fibrosis, cancer, immunological and infectious diseases. Glympse Bio’s can be administered in a minimally invasive manner and the analytical read-out can be selected based on the disease characteristics or market needs for the test, according to the company’s website. Its lead indication targets non-alcoholic steatohepatitis (NASH), which causes fibrosis and scarring of the liver and is believed to afflict more than 100 million people worldwide, including over 15 million in the United States alone. The company said it has signed multiple collaborations in NASH with pharmaceutical companie...
Source: Mass Device - Category: Medical Devices Authors: Tags: Bioelectronic Medicine Blog Business/Financial News Diagnostics Featured Funding Roundup Research & Development glympsebio Massachusetts Institute of Technology Source Type: news