Inactivated Orf-virus shows disease modifying antiviral activity in a guinea pig model of genital herpesvirus infection

ConclusioniORFV effectively suppressed recurrences in guinea pigs experimentally infected with HSV. iORFV did not only reduce recurrent disease episodes but was, compared with ACV, more effective in reducing latency as measured by viral DNA detected in dorsal root ganglia of infected animals.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research